journal cover

3' end mRNA processing: molecular mechanisms and implications for health and disease

The EMBO Journal

Feb 8, 2008

Sven DanckwardtAndreas E Kulozik

Abstract

Recent advances in the understanding of the molecular mechanism of mRNA 3' end processing have uncovered a previously unanticipated integrated network of transcriptional and RNA-processing mechanisms. A variety of human diseases impressively reflect the importance of the precision of th...read more

Mentioned in this Paper

MRNA Maturation
Transcription, Genetic
MRNA Processing
MRNA 3'-end Processing
Inflammation
Poly(A) Tail
Malignant Neoplasms
RNA 3' End Processing
259
1
Paper Details
References
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  • Citations124
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  • References178
  • Citations124
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3' end mRNA processing: molecular mechanisms and implications for health and disease

The EMBO Journal

Feb 8, 2008

Sven DanckwardtAndreas E Kulozik

PMID: 18256699

DOI: 10.1038/sj.emboj.7601932

Abstract

Recent advances in the understanding of the molecular mechanism of mRNA 3' end processing have uncovered a previously unanticipated integrated network of transcriptional and RNA-processing mechanisms. A variety of human diseases impressively reflect the importance of the precision of th...read more

Mentioned in this Paper

MRNA Maturation
Transcription, Genetic
MRNA Processing
MRNA 3'-end Processing
Inflammation
Poly(A) Tail
Malignant Neoplasms
RNA 3' End Processing
259
1

Similar Papers Found In These Feeds

European Molecular Biology Laboratory (EMBL)

The European Molecular Biology Laboratory (EMBL) research institution focusing on the fundamental understanding of basic biological processes in model organisms. Follow this feed to stay updated on research from the members of this institute.

Inflammation & Cancer

Inflammation has been implicated in initiation and progression of tumors, as well as elimination of cancerous cells. Here is the latest research on the role of inflammation in cancer.

Related Papers

Nucleic Acids Research

Molecular mechanisms of eukaryotic pre-mRNA 3' end processing regulation

Nucleic Acids ResearchJanuary 2, 2010
Stefania Millevoi, Stéphan Vagner
The EMBO Journal

Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals

The EMBO JournalApril 28, 2007
Sven DanckwardtAndreas E Kulozik
Paper Details
References
  • References178
  • Citations124
12345...
  • References178
  • Citations124
12345...
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