journal cover

Ω3 Supplementation and intermittent hypobaric hypoxia induce cardioprotection enhancing antioxidant mechanisms in adult rats

Marine Drugs

Feb 7, 2015

Emilio A HerreraRodrigo L Castillo

Abstract

Intermittent hypobaric hypoxia (IH) is linked with oxidative stress, impairing cardiac function. However, early IH also activate cardio-protective mechanisms. Omega 3 fatty acids (Ω3) induce cardioprotection by reducing infarct size and reinforcing antioxidant defenses. The aim of this ...read more

Mentioned in this Paper

Ischemia
Size
3-nitrotyrosine
Enzymes, antithrombotic
Left Ventricular Structure
Omega-3 Fatty Acids
Cardioassist
Energy Metabolism
Anti-Inflammatory Agents
Antioxidant Effect
1
23
Paper Details
References
  • References78
  • Citations6
12345...

Feeds With Similar Papers

Myocarditis

Myocarditis is an acute or chronic inflammatory disease of the myocardium which can be viral, postinfectious immune or primarily organ-specific autoimmune. Discover the latest research on myocarditis here.

SETD2 Functions (Keystone)

Histone methyltransferases (HMTs), as chromatin modifiers, regulate the transcriptomic landscape in normal development as well as in diseases such as cancer. Here is the latest research on SETD2 as a tumor suppressor with actin lysine methyltransferase activity.

Inotropic Agents & Heart Disease

Inotropic agents alter the force or energy of muscular contractions. Negatively inotropic agents weaken the force of muscular contractions. Positively inotropic agents increase the strength of muscular contraction. Inotropic agents are used in hospitalized patients with acute decompensated heart failure, with reduced left ventricular ejection fraction and with signs of end-organ dysfunction in the setting of a low cardiac output, or with severe systolic heart failure awaiting heart transplant to maintain hemodynamic stability or as a bridge to decision. Discover the latest research on inotrpic agents and heart diseases here.

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here

Hypoxia

Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level. Hypoxia may be classified as either generalized, affecting the whole body, or local, affecting a region of the body. Here is the latest research.

Renal Hypoxia & Ischemia

Acute renal failure is most commonly caused by ischemia. Ischemic-induced renal tissue hypoxia is thought to be a major component in the development of acute renal failure in promoting the initial tubular damage. Here is the latest research.

Ischemia & Reperfusion

Ischemia and reperfusion is a pathological condition characterized by an initial restriction of blood supply to an organ followed by the subsequent restoration of perfusion and concomitant reoxygenation. Restoration of blood flow and reoxygenation is frequently associated with an exacerbation of tissue injury and a profound inflammatory response (called ‘reperfusion injury’). Discover the latest research on ischemia and reperfusion here.

Related Papers

American Journal of Physiology. Heart and Circulatory Physiology

Role of oxidative stress in PKC-delta upregulation and cardioprotection induced by chronic intermittent hypoxia

American Journal of Physiology. Heart and Circulatory PhysiologyAugust 29, 2006
F KolarJan Herget
© 2020 Meta ULC. All rights reserved

Ω3 Supplementation and intermittent hypobaric hypoxia induce cardioprotection enhancing antioxidant mechanisms in adult rats

Marine Drugs

Feb 7, 2015

Emilio A HerreraRodrigo L Castillo

PMID: 25658050

DOI: 10.3390/md13020838

Abstract

Intermittent hypobaric hypoxia (IH) is linked with oxidative stress, impairing cardiac function. However, early IH also activate cardio-protective mechanisms. Omega 3 fatty acids (Ω3) induce cardioprotection by reducing infarct size and reinforcing antioxidant defenses. The aim of this ...read more

Mentioned in this Paper

Ischemia
Size
3-nitrotyrosine
Enzymes, antithrombotic
Left Ventricular Structure
Omega-3 Fatty Acids
Cardioassist
Energy Metabolism
Anti-Inflammatory Agents
Antioxidant Effect
1
23

Feeds With Similar Papers

Myocarditis

Myocarditis is an acute or chronic inflammatory disease of the myocardium which can be viral, postinfectious immune or primarily organ-specific autoimmune. Discover the latest research on myocarditis here.

SETD2 Functions (Keystone)

Histone methyltransferases (HMTs), as chromatin modifiers, regulate the transcriptomic landscape in normal development as well as in diseases such as cancer. Here is the latest research on SETD2 as a tumor suppressor with actin lysine methyltransferase activity.

Related Papers

American Journal of Physiology. Heart and Circulatory Physiology

Role of oxidative stress in PKC-delta upregulation and cardioprotection induced by chronic intermittent hypoxia

American Journal of Physiology. Heart and Circulatory PhysiologyAugust 29, 2006
F KolarJan Herget
Paper Details
References
  • References78
  • Citations6
12345...

Download from

Publisher
PubMed
/papers/3-supplementation-and-intermittent-hypobaric/25658050