3-Tesla MRI of deep brain stimulation patients: safety assessment of coils and pulse sequences

Journal of Neurosurgery
Alexandre BoutetAndres M Lozano

Abstract

OBJECTIVEPhysicians are more frequently encountering patients who are treated with deep brain stimulation (DBS), yet many MRI centers do not routinely perform MRI in this population. This warrants a safety assessment to improve DBS patients' accessibility to MRI, thereby improving their care while simultaneously providing a new tool for neuromodulation research.METHODSA phantom simulating a patient with a DBS neuromodulation device (DBS lead model 3387 and IPG Activa PC model 37601) was constructed and used. Temperature changes at the most ventral DBS electrode contacts, implantable pulse generator (IPG) voltages, specific absorption rate (SAR), and B1+rms were recorded during 3-T MRI scanning. Safety data were acquired with a transmit body multi-array receive and quadrature transmit-receive head coil during various pulse sequences, using numerous DBS configurations from "the worst" to "the most common."In addition, 3-T MRI scanning (T1 and fMRI) was performed on 41 patients with fully internalized and active DBS using a quadrature transmit-receive head coil. MR images, neurological examination findings, and stability of the IPG impedances were assessed.RESULTSIn the phantom study, temperature rises at the DBS electrodes were l...Continue Reading

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Citations

May 31, 2019·Current Neurology and Neuroscience Reports·Alexandre BoutetAlfonso Fasano
Oct 23, 2019·Brain Sciences·Keith StarnesBrian Nils Lundstrom
Jul 12, 2020·Journal of Parkinson's Disease·Joke M DijkRob M A de Bie
Nov 28, 2020·Nature Reviews. Neurology·Joachim K KraussAndres M Lozano
Dec 1, 2020·Annals of Neurology·Gavin J B EliasAndres M Lozano
Jan 26, 2021·Journal of Alzheimer's Disease : JAD·Yu-Si ChenHui-Cong Kang
Jun 30, 2021·Seminars in Pediatric Neurology·Travis LarshJennifer A O'Malley
Feb 15, 2020·Journal of Neurosurgery. Spine·Alexandre BoutetAndres M Lozano

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