3.0 T MRI of 2000 consecutive patients with localisation-related epilepsy.

The British Journal of Radiology
I CravenN Hoggard

Abstract

Clinical guidelines suggest that all patients diagnosed with localised seizures should be investigated with MRI to identify any epileptogenic structural lesions, as these patients may benefit from surgical resection. There is growing impetus to use higher field strength scanners to image such patients, as some evidence suggests that they improve detection rates. We set out to review the detection rate of radiological abnormalities found by imaging patients with localised seizures using a high-resolution 3.0 T epilepsy protocol. Data were reviewed from 2000 consecutive adult patients with localisation-related epilepsy referred between January 2005 and February 2011, and imaged at 3.0 T using a standard epilepsy protocol. An abnormality likely to be related to seizure activity was identified in 403/2000 (20.2%) patients, with mesial temporal sclerosis diagnosed in 211 patients. 313/2000 (15.6%) had lesions potentially amenable to surgery. Abnormalities thought unrelated to seizure activity were found in 324/2000 (16.1%), with 8.9% having evidence of ischaemic disease. Since the introduction of the then National Institute for Clinical Excellence guidelines in 2004, the detection rate of significant pathology using a dedicated 3.0 ...Continue Reading

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Citations

May 3, 2014·Annals of Indian Academy of Neurology·Aashit K Shah, Sandeep Mittal
Apr 9, 2014·Nature Reviews. Neurology·Jo M WilmshurstJ Helen Cross
Jun 10, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Anto Bagić
Jun 22, 2016·Seizure : the Journal of the British Epilepsy Association·Candice E CrockerMatthias H Schmidt
Oct 10, 2018·AJR. American Journal of Roentgenology·Eric TranvinhMax Wintermark
Jan 16, 2014·Clinical Neuroradiology·E AbelaR Wiest
Nov 19, 2013·Epilepsia·Charles MellerioCatherine Oppenheim
Dec 10, 2017·Annals of Global Health·Veronica BrunoUNKNOWN Bhutan Epilepsy Project
Jun 6, 2018·Journal of Clinical Medicine·Mehmet Alp Dirik, Burcin Sanlidag
May 28, 2019·Seizure : the Journal of the British Epilepsy Association·Csaba Juhász, Flóra John
Jun 9, 2021·Seizure : the Journal of the British Epilepsy Association·Christopher MarkosianLuke D Tomycz

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