3D cephalometric analysis using Magnetic Resonance Imaging: validation of accuracy and reproducibility

Scientific Reports
Alexander JuerchottSabine Heiland

Abstract

The aim of this study was to validate geometric accuracy and in vivo reproducibility of landmark-based cephalometric measurements using high-resolution 3D Magnetic Resonance Imaging (MRI) at 3 Tesla. For accuracy validation, 96 angular and 96 linear measurements were taken on a phantom in 3 different positions. In vivo MRI scans were performed on 3 volunteers in five head positions. For each in vivo scan, 27 landmarks were determined from which 19 angles and 26 distances were calculated. Statistical analysis was performed using Bland-Altman analysis, the two one-sided tests procedure and repeated measures one-way analysis of variance. In comparison to ground truth, all MRI-based phantom measurements showed statistical equivalence (p < 0.001) and an excellent agreement in Bland-Altman analysis (bias ranges: -0.090-0.044°, -0.220-0.241 mm). In vivo cephalometric analysis was highly reproducible among the five different head positions in all study participants, without statistical differences for all angles and distances (p > 0.05). Ranges between maximum and minimum in vivo values were consistently smaller than 2° and 2 mm, respectively (average ranges: 0.88°/0.87 mm). In conclusion, this study demonstrates that accurate and repr...Continue Reading

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Citations

May 10, 2019·The Laryngoscope·Arjun K ParasherNithin D Adappa
Sep 10, 2020·Scientific Reports·Hyo-Min ChoBongyoung Ahn
Jul 29, 2019·Clinical Oral Investigations·Alexander JuerchottTim Hilgenfeld
Jul 15, 2020·Clinical Oral Investigations·Balazs FeherUlrike Kuchler
Sep 28, 2021·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Kazlin N MasonJamie L Perry
Nov 6, 2021·Journal of Orofacial Orthopedics = Fortschritte Der Kieferorthopädie : Organ/official Journal Deutsche Gesellschaft Für Kieferorthopädie·Felix H BlankensteinDaniel Stelmaszczyk

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Methods Mentioned

BETA
X-ray

Software Mentioned

Xcode
Osirix
R Foundation for Statistical Computing
Amira
TOST
R
MAS
DICOM Imaging

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