3D computed tomography angiography as a novel post-processing approach in diagnosis of pediatric malignant bone tumors

Journal of X-ray Science and Technology
Jun WuYuanyuan Zhang

Abstract

This study aimed to investigate the application of 3D computed tomography (CT) angiography with a novel post-processing technique in diagnosis of malignant bone tumors in children. Twenty-seven pediatric patients (15 males and 12 females; average age: 10±3.4 years old, with a range from 2 months to 14 years old) with suspected bone tumors were evaluated histopathologically using 3D CT angiography and a multislice scanner. CT angiography image data were analyzed with a novel post-processing technique that included separating, fusing opacifying false-coloring, and volume rendering. Among 27 cases, 20 (74%) osteosarcoma, 6 (22%) Ewing's sarcoma, and 1 (4%) non-Hodgkin lymohoma were diagnosed by histological examination of surgical specimens. The tumor features, including size, location, invasion into the adjacent tissue as well as distant metastases, were clearly visualized with the regular volume rendering method and rotational and stereoscopical videos. The post-processing technique provided the reconstructed structure images without any overlap or shelter independently and collectively. Special colors represented different tissue structures, aiding in identification of various anatomical structures and pre-surgical planning. Co...Continue Reading

References

Jul 4, 1998·European Journal of Radiology·M CampanacciL Campanacci
Aug 12, 1999·Radiologic Clinics of North America·H J Van der Woude, G Vanderschueren
Feb 7, 2003·The New England Journal of Medicine·Peter AspelinUNKNOWN Nephrotoxicity in High-Risk Patients Study of Iso-Osmolar and Low-Osmolar Non-Ionic Contrast Media Study Investigators
May 13, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Laura M FayadElliot K Fishman
Jan 30, 2007·The British Journal of Surgery·M M ChowdhuryA Pierro
Jun 4, 2008·Sarcoma·R J GrimerR S Sneath
Nov 3, 2010·The Journal of Bone and Joint Surgery. British Volume·R J Grimer, T W R Briggs
Dec 18, 2010·Revue des maladies respiratoires·G-R Ferretti, A Jankowski
May 16, 2013·Seminars in Musculoskeletal Radiology·Mark J Kransdorf, Mellena D Bridges
Feb 4, 2014·CA: a Cancer Journal for Clinicians·Elizabeth WardAhmedin Jemal
Jul 30, 2014·Cancer Treatment and Research·Nicholas Morley, Imran Omar
Jun 8, 2015·Current Opinion in Oncology·Ty K Subhawong, Breelyn A Wilky
Dec 15, 2015·Radiologic Clinics of North America·Dominik FleischmannRichard Hallett

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Citations

Jan 16, 2021·Journal of Biophotonics·Caizhong GuanYaguang Zeng

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