3D free-breathing cardiac magnetic resonance fingerprinting.

NMR in Biomedicine
Gastão CruzClaudia Prieto

Abstract

To develop a novel respiratory motion compensated three-dimensional (3D) cardiac magnetic resonance fingerprinting (cMRF) approach for whole-heart myocardial T1 and T2 mapping from a free-breathing scan. Two-dimensional (2D) cMRF has been recently proposed for simultaneous, co-registered T1 and T2 mapping from a breath-hold scan; however, coverage is limited. Here we propose a novel respiratory motion compensated 3D cMRF approach for whole-heart myocardial T1 and T2 tissue characterization from a free-breathing scan. Variable inversion recovery and T2 preparation modules are used for parametric encoding, respiratory bellows driven localized autofocus is proposed for beat-to-beat translation motion correction and a subspace regularized reconstruction is employed to accelerate the scan. The proposed 3D cMRF approach was evaluated in a standardized T1 /T2 phantom in comparison with reference spin echo values and in 10 healthy subjects in comparison with standard 2D MOLLI, SASHA and T2 -GraSE mapping techniques at 1.5 T. 3D cMRF T1 and T2 measurements were generally in good agreement with reference spin echo values in the phantom experiments, with relative errors of 2.9% and 3.8% for T1 and T2 (T2 < 100 ms), respectively. in vivo l...Continue Reading

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Citations

Sep 26, 2020·Physics in Medicine and Biology·T BruijnenR H N Tijssen
Feb 27, 2021·Progress in Nuclear Magnetic Resonance Spectroscopy·Brendan L EckNicole Seiberlich
May 11, 2021·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Haikun QiClaudia Prieto
Aug 22, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Daniel J WestShaihan J Malik
Oct 4, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Gastao CruzClaudia Prieto

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