PMID: 15224863Jul 1, 2004Paper

3D micro-CT images of ossicles destroyed by middle ear cholesteatoma

Acta Oto-laryngologica
Keehyun ParkMyon Ghyun Baek

Abstract

To reconstruct the 3D structures of normal ossicles and ossicles destroyed by different cholesteatomas, and to compare the volume fractions of the two types of ossicles. Thirteen pathological ossicles from four kinds of middle ear cholesteatoma obtained during surgery were used. Normal ossicles harvested from cadaveric temporal bone specimens were used as controls. The structures of the ossicles were analyzed using micro-CT by filming 2D cross-sectional images perpendicular to the long axis, from which 3D images were reconstructed. The volume fraction was measured using a CT-Analyzer and Ant. The volume fraction, indicating the relative strength of normal ossicles, was lower in the portion close to the articular surface. As the four types of cholesteatoma were found to express their patterns of destruction at various sites in the ossicles, they revealed a different volume fraction in each ossicle. Our preliminary data on ossicular structure obtained using micro-CT will be helpful for elucidating the normal and pathological structure of ossicles and for the further development of artificial prostheses.

References

Jan 1, 1992·Acta Anatomica·R SarratJ Whyte
Jun 1, 2000·Journal of Dental Research·E B Giesen, T M van Eijden

❮ Previous
Next ❯

Citations

Oct 20, 2006·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Girish M FatterpekarPeter M Som
Jul 2, 2010·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Jeong-Hyun JeeByung Do Lee
Mar 11, 2011·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Sven HerkenhoffPingling Kwok

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.