3D MRI Modeling of Thin and Spatially Complex Soft Tissue Structures without Shrinkage: Lamprey Myosepta as an Example

The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology
Bradley M WoodDominique G Homberger

Abstract

3D imaging techniques enable the nondestructive analysis and modeling of complex structures. Among these, MRI exhibits good soft tissue contrast, but is currently less commonly used for nonclinical research than X-ray CT, even though the latter requires contrast-staining that shrinks and distorts soft tissues. When the objective is the creation of a realistic and complete 3D model of soft tissue structures, MRI data are more demanding to acquire and visualize and require extensive post-processing because they comprise noncubic voxels with dimensions that represent a trade-off between tissue contrast and image resolution. Therefore, thin soft tissue structures with complex spatial configurations are not always visible in a single MRI dataset, so that standard segmentation techniques are not sufficient for their complete visualization. By using the example of the thin and spatially complex connective tissue myosepta in lampreys, we developed a workflow protocol for the selection of the appropriate parameters for the acquisition of MRI data and for the visualization and 3D modeling of soft tissue structures. This protocol includes a novel recursive segmentation technique for supplementing missing data in one dataset with data from...Continue Reading

References

Jan 1, 1986·Stain Technology·W GarveyC Jimenez
Dec 1, 1953·Journal of the American Pharmaceutical Association·V H WALLINGFORD
Nov 2, 2004·Radiology·Joshua W StuhlfautErwin F Hirsch
Nov 22, 2005·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Ralf TunnDirk Beyersdorff
Sep 8, 2006·Plant Physiology·Maarten J ChrispeelsDonald R Ort
Jul 27, 2007·Breast Cancer Research and Treatment·Wei T YangMassimo Cristofanilli
Feb 25, 2009·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Brian D Metscher
Jan 23, 2010·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Elizabeth L BrainerdJoseph J Crisco
Mar 2, 2010·Circulation. Cardiovascular Imaging·Karl DegenhardtJonathan A Epstein
Sep 18, 2010·Journal of Biomechanics·Nathan S JefferyPhilip G Cox
Mar 30, 2011·PloS One·Henrik LauridsenMichael Pedersen
Oct 25, 2011·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Jacob RasmussenChristian von Buchwald
Jun 1, 2013·Journal of Anatomy·Paula VickertonNathan Jeffery
Aug 27, 2013·Odontology·Hidekazu AoyagiKenzirou Nakamura
Nov 23, 2013·AJR. American Journal of Roentgenology·Gillian MurphyBoraiah Sreeharsha
Jan 15, 2014·Journal of Manipulative and Physiological Therapeutics·Graham Scarr
Feb 1, 2014·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Paul M Gignac, Nathan J Kley
Mar 5, 2014·Pediatrics·Gudrun AspelundCarrie Ruzal-Shapiro
Jun 2, 2014·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Andrew D ScottMarc E Miquel
Jun 26, 2014·Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·Jan BuytaertJoris Dirckx
Mar 21, 2015·AJR. American Journal of Roentgenology·Antony RaikhlinRoberta Jong
Jun 9, 2015·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Michelle L Osborn, Dominique G Homberger
Jul 24, 2015·Radiology·Lucas L GeyerCarlo N De Cecco
Sep 26, 2015·Scientific Reports·Juliana Martins de S e SilvaFranz Pfeiffer
Feb 10, 2016·Computer Methods in Biomechanics and Biomedical Engineering·Gregor HarihBojan Dolšak
Dec 4, 2016·Biomechanics and Modeling in Mechanobiology·H MarouaneM Adouni
Oct 3, 2017·Journal of Pathology Informatics·Navid FarahaniLiron Pantanowitz
Dec 20, 2017·Cardiovascular Diagnosis and Therapy·Sandra S HalliburtonPrabhakar Rajiah

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biomechanics

Biomechanics examines the generation of internal forces within the body and investigates the effects and control of forces that act on or are produced on tissues. Here are the latest discoveries.

Related Papers

The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology
Frank Rühli
Biomedizinische Technik. Biomedical Engineering
C Hartung
The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology
Ellen Jensen
Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists
Alberto Prats-GalinoTatjana Stopar Pintarič
© 2022 Meta ULC. All rights reserved