3D Quantification of Wall Shear Stress and Oscillatory Shear Index Using a Finite-Element Method in 3D CINE PC-MRI Data of the Thoracic Aorta

IEEE Transactions on Medical Imaging
Julio SoteloDaniel E Hurtado

Abstract

Several 2D methods have been proposed to estimate WSS and OSI from PC-MRI, neglecting the longitudinal velocity gradients that typically arise in cardiovascular flow, particularly on vessel geometries whose cross section and centerline orientation strongly vary in the axial direction. Thus, the contribution of longitudinal velocity gradients remains understudied. In this work, we propose a 3D finite-element method for the quantification of WSS and OSI from 3D-CINE PC-MRI that accounts for both in-plane and longitudinal velocity gradients. We demonstrate the convergence and robustness of the method on cylindrical geometries using a synthetic phantom based on the Poiseuille flow equation. We also show that, in the presence of noise, the method is both stable and accurate. Using computational fluid dynamics simulations, we show that the proposed 3D method results in more accurate WSS estimates than those obtained from a 2D analysis not considering out-of-plane velocity gradients. Further, we conclude that for irregular geometries the accurate prediction of WSS requires the consideration of longitudinal gradients in the velocity field. Additionally, we compute 3D maps of WSS and OSI for 3D-CINE PC-MRI data sets from an aortic phant...Continue Reading

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Citations

Mar 13, 2016·Journal of Magnetic Resonance Imaging : JMRI·Jesús UrbinaSergio A Uribe
May 24, 2016·IEEE Transactions on Medical Imaging·Joaquin MuraSergio Uribe
Apr 4, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Julio SoteloSergio Uribe
Oct 6, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Julio SoteloSergio Uribe
Jul 18, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Cristian MontalbaSergio Uribe
Mar 21, 2017·Biomechanics and Modeling in Mechanobiology·Daniel E HurtadoAlejandro Bruhn
Apr 3, 2018·Journal of Magnetic Resonance Imaging : JMRI·Judith ZimmermannAnja Hennemuth
Sep 6, 2020·Magnetic Resonance Imaging·Sébastien LevillyJean-Michel Serfaty
Feb 20, 2021·Scientific Reports·Marco CastagnaDavid Le Touzé
May 14, 2021·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·David MarleviNicholas S Burris
Jun 3, 2021·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Albert ChongErik Groot Jebbink
Aug 23, 2021·Medical Image Analysis·David NolteCristóbal Bertoglio

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