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3D RNA and Functional Interactions from Evolutionary Couplings

Cell

Apr 19, 2016

Caleb WeinrebDebora S Marks

Abstract

Non-coding RNAs are ubiquitous, but the discovery of new RNA gene sequences far outpaces the research on the structure and functional interactions of these RNA gene sequences. We mine the evolutionary sequence record to derive precise information about the function and structure of RNAs...read more

Mentioned in this Paper

Muscle Rigidity
Exploration With a Probe
Research
Ribosomal Proteins
Ribonucleoprotein Activity
Genes
RNA, Untranslated
Riboswitch
Complex (molecular entity)
MT-TA gene
41
1
275
1
2
Paper Details
References
  • References93
  • Citations18
12345...
  • References93
  • Citations18
12

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3D RNA and Functional Interactions from Evolutionary Couplings

Cell

Apr 19, 2016

Caleb WeinrebDebora S Marks

PMID: 27087444

DOI: 10.1016/j.cell.2016.03.030

Abstract

Non-coding RNAs are ubiquitous, but the discovery of new RNA gene sequences far outpaces the research on the structure and functional interactions of these RNA gene sequences. We mine the evolutionary sequence record to derive precise information about the function and structure of RNAs...read more

Mentioned in this Paper

Muscle Rigidity
Exploration With a Probe
Research
Ribosomal Proteins
Ribonucleoprotein Activity
Genes
RNA, Untranslated
Riboswitch
Complex (molecular entity)
MT-TA gene
41
1
275
1
2

Similar Papers Found In These Feeds

Gene Evolution & Mutation

The identification of precise mutations is required for a complete understanding of the underlying molecular and evolutionary mechanisms driving adaptive phenotypic chang

Riboswitches and Ribozymes

Ribozymes are catalytic RNAs that interact with a variety of small molecule substrates and cofactors, the intracellular abundance of which are sensed by riboswitches that modulate transcription, RNA stability, or translation. Here is the latest research.

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ELife

Sequence co-evolution gives 3D contacts and structures of protein complexes

ELifeSeptember 26, 2014
Thomas A HopfDebora S Marks
Paper Details
References
  • References93
  • Citations18
12345...
  • References93
  • Citations18
12
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