PMID: 6163114Jan 1, 1981Paper

3H]Spiroperidol binding in normal and denervated carotid bodies

Neuroscience Letters
B DingerS Fidone

Abstract

Specific dopamine receptors were studied in freshly dissected, unhomogenized rabbit carotid bodies incubated in [3H]spiroperidol. Total binding and non-specific binding were determined in the absence and presence of 0.2 microM (+)-butaclamol, respectively. Specific binding in normal carotid bodies incubated at near saturating concentrations (0.38 nM) was 1.63 +/- 0.58 pmol/g of tissue. Chronic section of the carotid sinus nerve (14 days) resulted in a 64% reduction (P less than 0.05) in specific binding. We conclude that the majority of specific dopaminergic receptors are located on carotid sinus nerve afferent terminals.

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Citations

Apr 1, 1985·Brain Research·P Zapata, C Eyzaguirre
Jul 16, 1993·Brain Research·L Monti-BlochP Aguilera
Feb 1, 1982·Respiration Physiology·P Zapata, A Zuazo
Nov 1, 1992·Journal of the Autonomic Nervous System·M F Czyzyk-KrzeskaD E Millhorn
Oct 23, 1989·Neuroscience Letters·W J WangS J Fidone
May 28, 2005·Respiratory Physiology & Neurobiology·Aida Bairam, John L Carroll
Feb 21, 1998·Journal of the Autonomic Nervous System·J ChenS Fidone
Jan 1, 1990·The European Journal of Neuroscience·C. EyzaguirreJ. W. Woodbury
Jan 1, 1990·The European Journal of Neuroscience·A. R. Benot, J. López-Barneo
Nov 1, 1996·The European Journal of Neuroscience·T G CacheroC Gonzalez
Jul 1, 1991·Journal of Neurochemistry·M A Delpiano, H Acker
Aug 15, 2015·Acta histochemica·Jun WakaiYoshio Yamamoto
Nov 13, 2014·Frontiers in Physiology·Ana R NunesEmília C Monteiro
Oct 18, 2002·Microscopy Research and Technique·Estelle B Gauda
Aug 24, 2000·Journal of Applied Physiology·K A HueyF L Powell
Aug 4, 2007·Journal of Applied Physiology·J Prieto-LloretR J Rigual
Feb 12, 2021·Physiological Reviews·Rodrigo IturriagaVirend K Somers

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