4D Flow when and how?

La Radiologia medica
Yasuo Takehara

Abstract

4D Flow is an emerging MR technique enabling three-dimensional and cardiac phase-resolved flowmetry with ECG-gated phase-contrast MRI that increased the speed of data acquisitions, accuracy and robustness. The method is promoting researches in areas that have not been fully addressed before in the cardiovascular system, such as flowmetry of the bloodstream across the valves, within the heart chambers, complexed flow dynamics such as vortex, helical or retrograde. Wall shear stress and other potential biomarkers derived from 4D Flow are known to be related to vascular wall diseases such as atherosclerosis. In this review, fundamental concepts of 4D Flow technique and post-processing, benefits and limitations as well as its clinical applications are discussed, and the importance of quality control and validation of the method is emphasized. New ideas inspired by 4D Flow can help clinicians and MR scientists further understand the role of flow dynamics in health sciences, diseases and various aspects of cardiovascular physiology.

References

Nov 1, 2006·Journal of Biomechanics·A D JeaysD R Hose
Mar 19, 2009·European Journal of Gastroenterology & Hepatology·Daniel BarthelmesStephan M Jakob
Mar 13, 2014·Journal of Magnetic Resonance Imaging : JMRI·Takamichi IshikawaTsutomu Ogata
Nov 17, 2015·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Masaki TeradaMarcus Alley
Jul 1, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Mayu SakataNaoki Unno
Jan 31, 2017·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Atsushi FukuyamaTakafumi Kosugi
Jan 8, 2019·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Alex BrattJonathan W Weinsaft
Feb 26, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Liliana E MaNing Jin
Apr 23, 2019·Journal of Thoracic Imaging·Tara A RetsonAlbert Hsiao
Feb 6, 2020·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Masataka SugiyamaHiroyuki Kabasawa

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Citations

Jul 14, 2020·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Yasuo TakeharaAtsushi Nozaki
Sep 3, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Junpei KawamuraYasuhiro Okamoto

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