5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP

Bioorganic & Medicinal Chemistry Letters
R SulskyL K Kunselman

Abstract

5-Carboxamido-1,3,2-dioxaphosphorinanes have been identified as potent inhibitors of microsomal triglyceride-transfer protein. The 1,3,2-dioxaphosphorine functionality acted as a neutral and stable replacement for piperidine and piperidine N-oxide.

References

Feb 2, 1996·Journal of Medicinal Chemistry·D R MagninC P Ciosek

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Citations

Jul 24, 2012·Journal of Agricultural and Food Chemistry·Wei WangXiao-Song Tan
Aug 13, 2015·Pesticide Biochemistry and Physiology·Chongchong SunHaifeng Qian
Oct 30, 2007·ChemMedChem·Oliver RauManfred Schubert-Zsilavecz
Sep 30, 2020·CPT: Pharmacometrics & Systems Pharmacology·Hiroyuki TakitaAmin Rostami-Hodjegan
Jun 2, 2021·Organic & Biomolecular Chemistry·Guang-Xin RuGuang-Qin Gao
May 1, 2013·Journal of the American Chemical Society·Weidong RaoPhilip Wai Hong Chan

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