6-phosphogluconolactonase mutants of Escherichia coli and a maltose blue gene.

Journal of Bacteriology
S R Kupor, D G Fraenkel

Abstract

Mutants lacking an enzyme of the oxidative branch of the hexose monophosphate shunt, 6-phosphogluconolactonase (pgl), have been selected as a new class of glucose-negative derivatives of a phosphoglucose isomerase (pgi) mutant. Glucose negativity is not as complete as in mutants lacking phosphoglucose isomerase and glucose-6-phosphate dehydrogenase. Pgi(+), pgl(-) strains have been constructed by transduction and grow almost normally on glucose. Genetic mapping shows that pgl lies between chlD and att-lambda, in the same position as and identical with a blu gene described by Adhya and Schwartz. These blu mutants grown on maltose were recognized by their property to turn blue after treatment with iodine. It is not known how phosphogluconolactonase deficiency causes this reaction; it might be related to accumulation of 6-phosphogluconolactone.

References

Dec 1, 1967·Bacteriological Reviews·A L Taylor, C D Trotter
Nov 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·S AdhyaA Campbell
May 1, 1967·Journal of Bacteriology·D G Fraenkel, S R Levisohn
Sep 1, 1953·Biochimica Et Biophysica Acta·B L HORECKER, P Z SMYRNIOTIS

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Citations

Mar 19, 1973·Molecular & General Genetics : MGG·A BernsteinK Onodera
Mar 7, 1973·Nature: New Biology·A Toussaint, M Faelen
Jul 11, 1978·Molecular & General Genetics : MGG·A Ahmed, D Scraba
Dec 14, 2004·Microbiology and Molecular Biology Reviews : MMBR·Evelyn ZientzRoy Gross
Nov 16, 2010·Applied and Environmental Microbiology·William T BeesonMichael A Marletta
Dec 4, 2004·Journal of Bacteriology·Lynn C ThomasonJudah L Rosner
Jun 1, 2011·World Journal of Microbiology & Biotechnology·Saeed Tarighi, Parissa Taheri
Dec 31, 1976·Molecular & General Genetics : MGG·A Ahmed, E Johansen
Aug 8, 2019·Metabolic Engineering·Christopher P Long, Maciek R Antoniewicz
Jan 1, 1972·Molecular & General Genetics : MGG·B Rosenwirth
Aug 16, 2001·Biotechnology and Bioengineering·M Dauner, U Sauer
Mar 1, 1976·Bacteriological Reviews·B J BachmannA L Taylor
Jan 1, 1973·Journal of Bacteriology·M Silverman, M Simon
Nov 1, 1971·Journal of Bacteriology·S Adhya, M Schwartz
Jun 1, 1970·Bacteriological Reviews·A L Taylor
Aug 1, 1979·Journal of Bacteriology·R A Roehl, R T Vinopal
Dec 1, 1969·Journal of Bacteriology·B L Josephson, D G Fraenkel
Feb 1, 1977·Antimicrobial Agents and Chemotherapy·A NakazawaT Tamada
Jun 1, 1972·Virology·H Murialdo, L Siminovitch
Nov 28, 1971·Journal of Molecular Biology·W Boram, J Abelson
Jun 5, 1970·Biochemical and Biophysical Research Communications·K OnoderaA Bernstein
Dec 5, 1987·Journal of Molecular Biology·R J Redfield, A M Campbell
Dec 1, 1993·Microbiological Reviews·M Riley
Nov 23, 2006·Microbial Cell Factories·Zhijun WangGrzegorz Wegrzyn

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