68Ga-FAPI PET/CT Improves Therapeutic Strategy by Detecting a Second Primary Malignancy in a Patient With Rectal Cancer.

Clinical Nuclear Medicine
Haojun ChenQin Lin

Abstract

A 71-year-old man with pathologically confirmed rectal cancer underwent F-FDG PET/CT before radical operation, which showed multiple nodules with low uptake in bilateral pleura and 1 solitary pulmonary nodule with slight uptake in left lung. The subpleural nodule was diagnosed as benign lesion through the biopsy. Ga-labeled fibroblast-activation-protein inhibitor PET/CT was performed for further evaluation, which showed low uptake in bilateral subpleural nodules but focally increased uptake in the nodule of left lung. This nodule was found to be a primary lung adenocarcinoma by the CT-guided biopsy. A diagnosis of rectum and lung double primary malignancies was finally made.

References

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Nov 8, 2017·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Marjolein A HeuvelmansRozemarijn Vliegenthart
Dec 21, 2017·Clinical Nuclear Medicine·Mads Ryø JochumsenGitte Lund Nielsen
Apr 8, 2018·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Anastasia LoktevUwe Haberkorn
Apr 8, 2019·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Clemens KratochwilFrederik L Giesel
Jun 5, 2019·Clinical Nuclear Medicine·Kianoush Ansari-GilaniNikhil H Ramaiya
Jul 6, 2019·Clinical Nuclear Medicine·Kianoush Ansari-GilaniNikhil H Ramaiya

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Citations

Aug 19, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Darpan N PandyaThaddeus J Wadas
Dec 23, 2020·Clinical Nuclear Medicine·Punit SharmaShankaramurthy Gayana
Mar 30, 2021·Frontiers in Oncology·Shuailiang WangZhi Yang
Aug 17, 2021·Radiologic Clinics of North America·Christian MasonJason S Lewis

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