PMID: 25743840Mar 7, 2015Paper

8-year analysis of the prevalence of lymph nodes metastasis, oncologic and pregnancy outcomes in apparent early-stage malignant ovarian germ cell tumors

Asian Pacific Journal of Cancer Prevention : APJCP
Usanee ChatchotikawongNisarat Phithakwatchara

Abstract

To determine the rate of lymph node metastasis, oncologic and pregnancy outcomes in apparent early-stage malignant ovarian germ cell tumor (MOGCT). Medical records of apparent early-stage MOGCT patients undergoing primary surgical treatment at Siriraj Hospital, Bangkok, Thailand, between January 2006 and December 2013, were retrospectively reviewed. Thirty-eight patients had apparent stage I-II MOGCT. The mean age was 22.1±7.7 years (median, 20.8 years; range, 7.7-35.6 years). The mean tumor size was 17.8±6.5 cm with a median of 20 (range 4-30) cm. Three most common histopathologies were dysgerminoma (12 patients, 31.6%), immature teratoma (12 patients, 31.6%), and endodermal sinus tumor (6 patients, 15.8%). Twenty-seven of 38 patients underwent lymphadenectomy; 13 patients (48.2%) were stage IA and 8 patients (29.6%) were stage IC. The rate of retroperitoneal nodes metastasis was 7.4% (2/27 patients). At 26.1 months of median follow-up time (range 1.9-88.5 months), 9 patients retained fertility functions, with uneventful pregnancies in 3 of these. Only one patient (2.6%) had progression of disease at 4.9 months after surgery. The 5-year survival rate was 97.4%. As the rate of pelvic or para-aortic node metastasis in MOGCT is c...Continue Reading

References

Feb 22, 2005·Gynecologic Oncology·Chyong-Huey LaiPo-Nan Wang
Aug 9, 2006·Current Opinion in Oncology·Daniel M Patterson, Gordon J S Rustin
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Jul 8, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Vithida Neeyalavira, Prapaporn Suprasert

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Citations

Apr 8, 2020·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Huzheng YanFujun Zhang
Apr 19, 2019·Journal of Cancer Survivorship : Research and Practice·Brigitte GerstlAntoinette Anazodo

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