99mTc-DTPA-galactosyl-human-serum-albumin liver scintigraphy for evaluating hepatic functional reserve before hepatectomy in a patient with indocyanine green excretory defect: report of a case.

Surgery Today
Jun KadonoRyuzo Sakata

Abstract

A 78-year-old woman with indocyanine green (ICG) excretory defect underwent left hepatectomy for cystadenocarcinoma. The retention rate of ICG at 15 min (ICGR(15)) was high, at 79.3%, despite all other liver function tests showing normal values. Conversely, 99mTc-DTPA-galactosyl-human-serum-albumin (GSA) liver scintigraphy showed a reduced accumulation of GSA in the left lateral lobe, the hepatic uptake ratio of the GSA scintigraphy was 0.96, and the arterial ketone body ratio was 1.67. Based on these results, we judged that the hepatic functional reserve of this patient was adequate for left hepatectomy, which was subsequently performed uneventfully. Histopathological examination of the resected liver showed neither fibrosis nor inflammatory cell infiltration. Thus, we consider that GSA liver scintigraphy is the best diagnostic modality for evaluating hepatic functional reserve in a patient with ICG excretory defect.

References

Mar 1, 1991·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·B MeyerG A Stalder
Jan 1, 1982·Gastroenterologia Japonica·S TakaseY Matsuda
Feb 1, 1997·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A H KwonY Kamiyama
Mar 26, 2004·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Atsushi NanashimaYouji Ogawa

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Citations

Jun 8, 2013·World Journal of Gastroenterology : WJG·Tatsuaki SumiyoshiKiminori Uka
Feb 1, 2013·Clinical Journal of Gastroenterology·Hideki AokiHitoshi Takeuchi
Mar 24, 2009·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·G GarceaG J Maddern
Jan 15, 2018·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·Ikuo NakamuraJiro Fujimoto
Jun 28, 2018·Japanese Journal of Radiology·Tatsuaki SumiyoshiManabu Matsumoto
Apr 14, 2021·The Journal of International Medical Research·Wei LiuXuan Qiu

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