(99m)Technetium-macroaggregated albumin perfusion lung scan versus contrast enhanced echocardiography in the diagnosis of the hepatopulmonary syndrome in children with chronic liver disease

European Journal of Gastroenterology & Hepatology
Mortada Hassan El-ShabrawiHanaa M El-Karaksy

Abstract

The hepatopulmonary syndrome (HPS) is a triad of advanced chronic liver disease (CLD), arterial hypoxemia and intrapulmonary arteriovenous shunting in the absence of a primary cardiopulmonary disease. HPS has been more frequently reported in adults than in children with no data on its prevalence in children with CLD. The aim of this study was to detect the prevalence of the HPS in a cohort of children with CLD because of chronic hepatitis B and/or C virus infection, schistosomiasis as well as inborn metabolic errors. We also aimed to evaluate the role of Technetium labeled macroaggregated albumin (Tc--MAA) perfusion lung scan versus contrast enhanced echocardiography (CEE) with intravenous injection of agitated saline in the diagnosis and quantification of intrapulmonary shunts and their relationship to important clinical and laboratory findings. Forty Egyptian children (22 males) were investigated. Their ages ranged from 5 to 12 years (with a mean of 9.5 years). Twenty individuals proved to have cirrhosis. Blood gas determination revealed more significant arterial hypoxemia in cirrhotics than noncirrhotics both under room air and after breathing 100% oxygen for 15 mins. CEE showed comparable cardiac measurements in cirrhotic a...Continue Reading

References

Sep 1, 1977·Chest·T C Kennedy, R J Knudson
Mar 12, 1999·The Surgical Clinics of North America·V L ScottY Kang
Sep 26, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M B Fallon, G A Abrams
Jan 5, 2001·Baillière's Best Practice & Research. Clinical Gastroenterology·L S Aboussouan, J K Stoller
Nov 2, 2004·The European Respiratory Journal·R Rodríguez-RoisinUNKNOWN ERS Task Force Pulmonary-Hepatic Vascular Disorders (PHD) Scientific Committee
Apr 14, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Karen L SwansonMichael J Krowka
Dec 6, 2005·Journal of the Chinese Medical Association : JCMA·Ying-Wen Wang, Han-Chieh Lin
Apr 22, 2006·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Federico P GómezRobert Rodríguez-Roisin
Apr 28, 2006·BMC Gastroenterology·Peter DeibertHubert Erich Blum
Apr 26, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Nitika Arora GuptaRene Romero
Mar 4, 2008·Pediatrics·Khalid NoliSimon C Ling
Feb 3, 2009·Vascular Health and Risk Management·Vincent Ho

❮ Previous
Next ❯

Citations

Jul 4, 2012·Nature Reviews. Gastroenterology & Hepatology·Junlan Zhang, Michael B Fallon
May 17, 2011·Annals of Thoracic Medicine·Ali Nawaz KhanAlaa Gouda
Jun 27, 2014·PLoS Neglected Tropical Diseases·Andréa Simone Siqueira de QueirósEdmundo Pessoa Almeida Lopes
Feb 7, 2012·Revue de pneumologie clinique·J BouguilaL Boughammoura
Mar 4, 2015·Digestive Diseases and Sciences·Yong Lv, Daiming Fan
Oct 19, 2014·Annals of Nuclear Medicine·Andréa Simone Siqueira de QueirósAna Lúcia Coutinho Domingues
Sep 6, 2011·Radiologic Clinics of North America·Frederick D Grant, S Ted Treves
Jul 26, 2018·European Journal of Gastroenterology & Hepatology·Marília R CezaGabriela P Coral
Aug 6, 2010·European Journal of Gastroenterology & Hepatology·Sam J ThomsonTony M Rahman
Jan 11, 2019·Journal of Pediatric Gastroenterology and Nutrition·Valérie A McLinUNKNOWN Members of the International Registry of Congenital Porto-Systemic Shunts
Oct 16, 2010·European Journal of Gastroenterology & Hepatology·George Kalambokis, Epameinondas V Tsianos
Oct 30, 2014·Liver International : Official Journal of the International Association for the Study of the Liver·Vibhor V BorkarSurender K Yachha
Feb 20, 2021·Scientific Reports·Kwang Yeon KimJae Sung Ko
Feb 20, 2021·Journal of Pediatric Gastroenterology and Nutrition·Nathalie M RockAlbane B R Maggio

❮ Previous
Next ❯

Related Concepts

Related Papers

European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology
María J RollánJosé L Bratos
São Paulo Medical Journal = Revista Paulista De Medicina
Liana Gonçalves de Macêdo, Edmundo Pessoa de Almeida Lopes
© 2021 Meta ULC. All rights reserved