A 1463 gene cattle-human comparative map with anchor points defined by human genome sequence coordinates

Genome Research
Annelie Everts-van der WindHarris A Lewin

Abstract

A second-generation 5000 rad radiation hybrid (RH) map of the cattle genome was constructed primarily using cattle ESTs that were targeted to gaps in the existing cattle-human comparative map, as well as to sparsely populated map intervals. A total of 870 targeted markers were added, bringing the number of markers mapped on the RH(5000) panel to 1913. Of these, 1463 have significant BLASTN hits (E < e(-5)) against the human genome sequence. A cattle-human comparative map was created using human genome sequence coordinates of the paired orthologs. One-hundred and ninety-five conserved segments (defined by two or more genes) were identified between the cattle and human genomes, of which 31 are newly discovered and 34 were extended singletons on the first-generation map. The new map represents an improvement of 20% genome-wide comparative coverage compared with the first-generation map. Analysis of gene content within human genome regions where there are gaps in the comparative map revealed gaps with both significantly greater and significantly lower gene content. The new, more detailed cattle-human comparative map provides an improved resource for the analysis of mammalian chromosome evolution, the identification of candidate gen...Continue Reading

References

Oct 1, 1992·Annals of Medicine·M Boehnke
Feb 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·J H Nadeau, B A Taylor
Feb 1, 1994·Genetics·M D BishopJ Yoo
Mar 1, 1994·Nature Genetics·W BarendseN Zhang
Jul 1, 1996·The Journal of Heredity·R Z MaH A Lewin
Jan 1, 1997·Mammalian Genome : Official Journal of the International Mammalian Genome Society·W BarendseL Lil
Mar 1, 1997·Genome Research·S M KappesC W Beattie
Jan 1, 1997·Mammalian Genome : Official Journal of the International Mammalian Genome Society·J E WomackY P Yang
Jan 1, 1997·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·D SlonimE Lander
Jul 10, 1998·Mammalian Genome : Official Journal of the International Mammalian Genome Society·R Z MaH A Lewin
Dec 30, 1999·Genome Research·G MontefalconeN Archidiacono
Aug 23, 2000·Animal Biotechnology·M Rebeiz, H A Lewin
Sep 14, 2000·Genome Research·M R BandH A Lewin
Apr 3, 2001·Genome Research·M VenturaM Rocchi
Jan 31, 2002·Trends in Genetics : TIG·James W Thomas, Jeffrey W Touchman
Feb 21, 2002·Proceedings of the National Academy of Sciences of the United States of America·Tom GoldammerJames E Womack
Jul 24, 2002·Proceedings of the National Academy of Sciences of the United States of America·Haruko TakedaTetsuo Kunieda
Sep 13, 2002·Mammalian Genome : Official Journal of the International Mammalian Genome Society·John L WilliamsDave Waddington
Nov 7, 2002·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Anette RinkCraig W Beattie
Dec 6, 2002·Nature·UNKNOWN Mouse Genome Sequencing ConsortiumEric S Lander
Jan 29, 2003·Proceedings of the National Academy of Sciences of the United States of America·Mark S SpringerStephen J O'Brien
Apr 18, 2003·Proceedings of the National Academy of Sciences of the United States of America·Richard GuyonElaine A Ostrander
Jun 18, 2003·Proceedings of the National Academy of Sciences of the United States of America·Pavel Pevzner, Glenn Tesler
Aug 7, 2003·Genome Research·Denis M LarkinHarris A Lewin

❮ Previous
Next ❯

Citations

Sep 24, 2005·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Candice Brinkmeyer-LangfordBhanu P Chowdhary
Oct 26, 2005·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Abdol Rahim AbbasiTetsuo Kunieda
Feb 6, 2008·Biochemical Genetics·H GuoH-Y Ren
Sep 20, 2005·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Jiri RubesTom Goldammer
Jan 6, 2007·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Tom GoldammerKlaus Wimmers
May 26, 2007·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Takahiro MurakamiKiyokazu Agata
Aug 3, 2007·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Gabriel BalmusMalcolm A Ferguson-Smith
Apr 25, 2008·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Tsuyoshi KobayashiAsato Kuroiwa
Oct 4, 2012·Animal : an International Journal of Animal Bioscience·S SeoJ J Loor
Sep 16, 2008·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Max A Alekseyev
Feb 17, 2009·Genome Research·Max A Alekseyev, Pavel A Pevzner
Jul 15, 2009·Genome Research·Harris A LewinStephen J O'Brien
Nov 9, 2005·Cytogenetic and Genome Research·E E ConnorJ L Williams
Feb 18, 2006·Cytogenetic and Genome Research·D M LarkinN S Zhdanova
Feb 3, 2007·Cytogenetic and Genome Research·R WeikardC Kuehn
Feb 3, 2007·Cytogenetic and Genome Research·T C van StijnS M Galloway
Dec 28, 2007·Cytogenetic and Genome Research·M N MiziaraM E J Amaral
Oct 22, 2008·Cytogenetic and Genome Research·T RaudseppB P Chowdhary
Aug 31, 2011·Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation·T RaudseppB P Chowdhary
Apr 28, 2009·BMC Genetics·Juan A AriasRichard Spelman
Aug 12, 2010·BMC Genomics·Jianfeng GaoRunlin Z Ma
Jun 10, 2005·BMC Genomics·Warren M SnellingTimothy P L Smith
Aug 19, 2007·Genome Biology·Warren M SnellingUNKNOWN International Bovine BAC Mapping Consortium
Dec 2, 2010·Genome Biology·Max A Alekseyev, Pavel A Pevzner
Nov 14, 2007·PLoS Computational Biology·Max A Alekseyev, Pavel A Pevzner
May 30, 2013·PloS One·Stefanie WaltherUlrike S Diesterbeck
Jan 7, 2014·PloS One·Natalya G AndreyenkovaElena S Belyaeva
Aug 28, 2007·Genetics·Mathieu GautierAndré Eggen
Dec 13, 2005·Proceedings of the National Academy of Sciences of the United States of America·Annelie Everts-van der WindHarris A Lewin
Nov 11, 2010·Journal of Applied Genetics·L De LorenziP Parma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
Annelie Everts-van der WindHarris A Lewin
Mammalian Genome : Official Journal of the International Mammalian Genome Society
John L WilliamsDave Waddington
© 2022 Meta ULC. All rights reserved