PMID: 8968690Sep 1, 1996Paper

A 15 year follow-up study of patients with non-insulin dependent diabetes mellitus (NIDDM) in Osaka, Japan. Long-term prognosis and causes of death

Diabetes Research and Clinical Practice
A SasakiT Shimizu

Abstract

A 15 year follow-up study of diabetic patients was performed in Osaka, Japan. The subjects studied were 1939 patients with non-insulin dependent diabetes mellitus (NIDDM), of whom 1000 (51.5%) were alive, 880 (45.4%) had died and 59 (3.0%) were untraceable at the end of 1993. The mortality rate per 1000 person-years of the subjects increased from 28.94 in 1960-1984 to 35.74 in 1985-1993, but the ratio of numbers of observed to expected deaths (O/E ratio) declined from 1.77 to 1.52 for the corresponding periods, suggesting an improvement in the prognosis for diabetic patients, with the exception of patients 65 years or over at the time of entry. Cerebro-cardiovascular and renal diseases were major causes of death, accounting for 48.4% of all deaths. In particular, disease of the heart was the cause of death in 20.5% of all deaths, cerebrovascular disease in 14.5% and renal disease in 12.0%. The O/E ratio was 11.30 for renal disease, which was remarkably high. The O/E ratios were 1.48 for malignant neoplasms, 3.02 for cancer of the liver and 2.15 for cancer of the pancreas. In the subjects less than 65 years of age at entry, a significant decrease in the O/E ratio for overall deaths, malignant neoplasms, disease of the heart, cer...Continue Reading

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Oct 1, 1994·Diabetes Research and Clinical Practice·A Sasaki

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Citations

Jun 21, 2001·Biochemical and Biophysical Research Communications·R K Naz, X Zhu
Oct 3, 2001·Diabetes Research and Clinical Practice·J C ChanC S Cockram
Aug 12, 2014·Japanese Journal of Clinical Oncology·Keitaro TanakaUNKNOWN Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan
Aug 25, 2004·Current Medical Research and Opinion·Andrew J PalmerGiatgen A Spinas
Dec 18, 2001·Diabetes/metabolism Research and Reviews·Y FujinoT Yoshimura
Nov 14, 2016·PharmacoEconomics·Michael WillisChristian Asseburg
May 31, 2013·Journal of Medical Economics·Michael WillisJianming He

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