A 17-year-old male with pseudotumor cerebri secondary to performance-enhancing steroids triggering venous thrombosis in the brain

Clinical Pediatrics
Allen D DeSena, Stephen Weimer

Abstract

This article is a case report of a 17-year-old male who presented with a headache and blurry vision. He subsequently was noted to have papilledema on a fundoscopic examination and an initial normal magnetic resonance imaging and computed tomography of his head; his condition was, therefore, diagnosed as pseudotumor cerebri. A subsequent magnetic resonance venography of his head revealed venous thrombosis, and other investigations revealed an elevated factor VIII level as well as a mutation at the MTHFR locus, consistent with an elevated risk for hypercoagulability. In addition, he admitted to steroid usage for purposes of performance enhancement in baseball. The patient's condition eventually improved with acetazolamide and serial lumbar punctures. Steroids have been linked to predisposition to hypercoagulable states, but there are no reports identified by these authors that link performance-enhancing steroids with pseudotumor cerebri as a result of a coagulation dyscrasia.

References

Aug 1, 1995·American Journal of Hematology·G S FerenchickK A Schwartz
Apr 1, 1994·Journal of Child Neurology·P BabikianW Bell
May 1, 1997·Headache·D J CapobiancoW P Cheshire
Jan 7, 1998·Clinical Pediatrics·N CondulisT O Carpenter
Sep 23, 1998·Pediatric Neurology·T Keren, E Lahat
Feb 25, 1999·American Journal of Ophthalmology·C SpeerM X Repka
Mar 11, 1999·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·A G QuinnJ R Buncic
Jun 16, 1999·The Annals of Pharmacotherapy·J A Fort, L D Smith
Aug 26, 2000·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M J Jakobczyk-ZmijaG K Lang
Feb 24, 2001·Journal of Child Neurology·A I Quintero-Del-Rio, Van Miller
Jan 21, 2003·Journal of Neurology·Ethem Murat ArsavaT Kansu
Jun 1, 1964·JAMA : the Journal of the American Medical Association·A E WALKER, J J ADAMKIEWICZ
Oct 26, 2005·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Charles J GlueckPing Wang
Jan 5, 2006·Indian Journal of Pediatrics·S BalasubramanianR Ganesh
Dec 7, 2007·Pediatric Neurology·Euthymia VargiamiMiranda Athanasiou-Metaxa

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Related Papers

Arquivos brasileiros de oftalmologia
Leonardo Provetti CunhaMário Luiz Ribeiro Monteiro
Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
R KrishnaK W Wright
Cleveland Clinic Journal of Medicine
D ChangW E Smith
© 2021 Meta ULC. All rights reserved