PMID: 2494978Mar 1, 1989Paper

A 2 year experience of a nutritional support service: prospective study of 229 non-intensive care patients receiving parenteral nutrition

The Australian and New Zealand Journal of Surgery
J P Fletcher, J M Mudie

Abstract

During a 2 year period, 229 non-intensive care patients received total parenteral nutrition (TPN) for a mean of 23.2 days. Nutritional parameters of weight, triceps skin-fold thickness (TSF), mid-arm muscle circumference (MAMC), total lymphocyte count (TLC), serum albumin and serum transferrin were measured prior to commencement of TPN and then at weekly intervals. All parameters showed an upward trend during the period of TPN. This was small and not statistically significant for weight, TSF, MAMC and albumin; the trends were greater and statistically significant for transferrin (P = 0.001) and TLC (P = 0.002). In contrast, in the 14.4% of patients who died, albumin, transferrin and TLC all fell. Patients who died had a significantly lower initial albumin (P = 0.05), transferrin (P = 0.04) and TLC (P = 0.04). The last values obtained in patients who died were very significantly lower for albumin (P less than 0.001), transferrin (P less than 0.001) and TLC (P = 0.003). Single-lumen tunnelled subclavian catheters had a significantly lower incidence of catheter sepsis (4.8%) compared with double-lumen (17.4%) and triple-lumen (13.7%) catheters (P = 0.01). There was also a greater incidence of mechanical and thrombotic complication...Continue Reading

References

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Sep 1, 1986·The Australian and New Zealand Journal of Surgery·J P Fletcher, J M Little
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Citations

Feb 1, 1994·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·P R GrayM Irving

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