A 20 years of progress and future of quantitative magnetic resonance imaging (qMRI) of cartilage and articular tissues-personal perspective

Seminars in Arthritis and Rheumatism
Felix Eckstein, Charles Peterfy

Abstract

In 1994, the first article on quantitative magnetic resonance imaging (qMRI) of articular cartilage was published, and tremendous progress in image acquisition, image analysis, and applications has since been made. The objective of this personal perspective is to highlight milestones in the field of qMRI of cartilage and other articular tissues over these past 20 years. Based on a Pubmed search of original articles, the authors selected 30 articles which they deemed to be among the first to provide an important technological step forward in qMRI of cartilage, provided a first application in a particular context, or provided mechanistic insight into articular cartilage physiology, pathology, or treatment. This personal perspective summarizes results from these 30 articles. Further, the authors provide examples of how qMRI of cartilage has translated to quantitative analysis approaches of other articular tissues, including bone, meniscus, and synovium/edema. Eventually, the report provides a summary of how the lessons learned might be applied to future clinical trials and clinical practice. Over the past 20 years, quantitative imaging of articular tissues has emerged from a method to a dynamic field of research by its own. Contin...Continue Reading

References

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Citations

May 20, 2020·Radiology·Frank W RoemerAli Guermazi
Dec 23, 2017·The British Journal of Radiology·Daichi HayashiAli Guermazi

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