A 30-year survey of drug use in the 1914 birth cohort in Glostrup County, Denmark: 1964-1994

Aging Clinical and Experimental Research
Elmo Jensen, Marianne Schroll

Abstract

Use of drugs increases with age. Several drugs as well as multiple drug intake are recognized risk factors for symptoms, disability, hospitalizations, and even mortality, due to side effects and problems with compliance. Yet, little is known about the long-term effects. As a first step, this longitudinal study of a general population gives insight into consumption patterns including multiple drug intake ("polypharmacy") and individual adherence to drug use over a 30-year period. This is a study based on the first large longitudinal population study of the health of adult Danes. Examinations were performed at 50, 60, 70 and 80 years of age. The Statistical Package for the Social Sciences (SPSS) was used to check participants' individual adherence to each of six main drug categories, calculated stepwise. 802 persons were included at 50 years of age in 1964. Of these, 213 were still participating in the study in 1994. The general use of drugs increased for all drug categories with age. Women used statistically significantly more drugs than men and showed a higher degree of polypharmacy. The individual adherence to antihypertensives was greater than the corresponding adherences to analgesics, psychoactive drugs, or hypnotics. At le...Continue Reading

References

Feb 15, 1986·Hospital Practice·L Williams, D R Rush
May 1, 1996·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·D SporeC Hawes
Feb 27, 1999·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·B Mehl, J P Santell
Sep 1, 2000·Journal of the American Geriatrics Society·C M HughesA Sgadari
Oct 26, 2000·European Journal of Clinical Pharmacology·I BaratE M Damsgaard
May 30, 2001·Journal of Human Hypertension·G OnderUNKNOWN Investigators of the GIFA Study (SIGG-ONLUS)
Dec 26, 2001·Archives of Internal Medicine·F LandiR Bernabei
Dec 11, 2002·Journal of the American Geriatrics Society·Graziano OnderGiovanni Gambassi
Jan 1, 1996·Pharmacoepidemiology and Drug Safety·L BowmanC D Black
Jul 3, 2004·BMJ : British Medical Journal·Munir PirmohamedAlasdair M Breckenridge
Aug 18, 2004·Advances in Therapy·Massimo Volpe
Jun 21, 2005·Zeitschrift für Gerontologie und Geriatrie·M Vass, C Hendriksen
Sep 30, 2005·Journal of Gerontological Nursing·Susan C Frazier

❮ Previous
Next ❯

Citations

Dec 3, 2010·BMC Clinical Pharmacology·Bo HovstadiusGöran Petersson
Sep 17, 2013·Pharmacoepidemiology and Drug Safety·P FriskB Wettermark
Mar 4, 2015·International Archives of Occupational and Environmental Health·Ute LatzaEva-Maria Backé
Jan 26, 2011·Pharmacoepidemiology and Drug Safety·Alessandro NobiliLuca Merlino

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.