Abstract
Use of drugs increases with age. Several drugs as well as multiple drug intake are recognized risk factors for symptoms, disability, hospitalizations, and even mortality, due to side effects and problems with compliance. Yet, little is known about the long-term effects. As a first step, this longitudinal study of a general population gives insight into consumption patterns including multiple drug intake ("polypharmacy") and individual adherence to drug use over a 30-year period. This is a study based on the first large longitudinal population study of the health of adult Danes. Examinations were performed at 50, 60, 70 and 80 years of age. The Statistical Package for the Social Sciences (SPSS) was used to check participants' individual adherence to each of six main drug categories, calculated stepwise. 802 persons were included at 50 years of age in 1964. Of these, 213 were still participating in the study in 1994. The general use of drugs increased for all drug categories with age. Women used statistically significantly more drugs than men and showed a higher degree of polypharmacy. The individual adherence to antihypertensives was greater than the corresponding adherences to analgesics, psychoactive drugs, or hypnotics. At le...Continue Reading
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