A 3D graphical representation of protein sequences based on the Gray code

Journal of Theoretical Biology
Ping-an HeYuhua Yao

Abstract

Based on the order of 6-bit binary Gray code, a cyclic order of 20 amino acids is introduced. A novel 3D graphical representation of protein sequences is proposed according to the CGR of DNA sequences. Furthermore, the mathematical descriptor is suggested to characterize the graphical representation curve. The efficiency of our approach can be illustrated by performing the comparison of similarities/dissimilarities among sequences of the ND5 proteins of nine different species. With the correlation and significance analysis, the comparisons of both our results and results of other graphical representation with the ClustalW's results can show the utility of our approach.

References

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Citations

Jul 16, 2014·BioMed Research International·Yusheng BaiPing-an He
Apr 23, 2016·SAR and QSAR in Environmental Research·A El-Lakkani, M Lashin
Dec 19, 2012·Mathematical Biosciences·Nafiseh Jafarzadeh, Ali Iranmanesh
Dec 9, 2014·Computers in Biology and Medicine·Zhao-Hui QiJun Feng
Oct 7, 2018·Journal of Mathematical Biology·Li GeMatthias Dehmer

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