A 4-year-old girl with clinically mild encephalopathy with a reversible splenial lesion associated with rotavirus infection

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Tatsuo FuchigamiMitsutaka Kuzuya

Abstract

Rotavirus is a common cause of severe gastroenteritis in children. It is known that rotavirus gastroenteritis may be accompanied by neurological manifestations, including encephalitis/encephalopathy and seizures. We report a case of a 4-year-old girl with clinically mild encephalopathy with a reversible splenial lesion associated with rotavirus infection. She was admitted to our hospital because of reduced level of consciousness, seizures, diarrhea, and vomiting. Fecal rotavirus antigen testing was positive. Cell counts in the cerebrospinal fluid (CSF) were normal. She had a normal serum sodium level on admission. Brain computed tomography showed no cerebral edema. However, electroencephalography showed generalized high-voltage slow waves, and diffusion-weighted magnetic resonance imaging demonstrated a transient abnormality in the splenium of the corpus callosum. We diagnosed clinically mild encephalopathy with a reversible splenial lesion associated with rotavirus infection. She recovered well and exhibited no neurological sequelae. Rotavirus RNA and antigen were not detected in the CSF, suggesting that the reversible splenial change was caused by indirect effects on the central nervous system subsequent to viral infection. H...Continue Reading

References

May 1, 2001·Journal of Paediatrics and Child Health·P N GoldwaterJ Bear
Aug 31, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M LynchR I Glass
Aug 10, 2005·The Journal of Infectious Diseases·Toyoko NakagomiPaul E Kilgore
Dec 1, 2006·Neuroradiology·Ji Hyun KimYounghen Lee
Feb 20, 2007·Brain & Development·Jun NatsumeTamiko Negoro
May 21, 2008·Brain & Development·Jun-ichi TakanashiA James Barkovich
Jan 13, 2009·Pediatric Neurology·Seiji FukudaSeiji Yamaguchi
Oct 13, 2009·The Journal of Infectious Diseases·Umesh D ParasharRoger I Glass
May 29, 2010·AJNR. American Journal of Neuroradiology·J TakanashiA J Barkovich
Jan 12, 2011·The Pediatric Infectious Disease Journal·Manish M PatelUmesh D Parashar
Apr 20, 2011·Pediatrics International : Official Journal of the Japan Pediatric Society·Toshihiko MoriHiroyuki Tsustumi

❮ Previous
Next ❯

Citations

Mar 4, 2014·Radiologic Clinics of North America·Toshio MoritaniBruno Policeni
Jul 2, 2015·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Jing Jing PanYang Yang
May 18, 2016·The Journal of Infection·Irene Rivero-CalleFederico Martinón-Torres
Oct 27, 2015·BMC Infectious Diseases·Konstantinos KarampatsasAndrew J Prendergast
Jun 28, 2017·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Marinos KontzialisThierry A G M Huisman
Feb 1, 2015·Journal of Child Neurology·Ki Won OhKyung Yeon Lee
Oct 8, 2019·Brain and Behavior·Syuichi Tetsuka
Jan 30, 2018·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·A V TitovE Yu Soloveva
Jan 3, 2021·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Kiyoshi KyoIchiro Morioka

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.