A 4D global respiratory motion model of the thorax based on CT images: A proof of concept

Medical Physics
Hadi FayadDimitris Visvikis

Abstract

Respiratory motion reduces the sensitivity and specificity of medical images especially in the thoracic and abdominal areas. It may affect applications such as cancer diagnostic imaging and/or radiation therapy (RT). Solutions to this issue include modeling of the respiratory motion in order to optimize both diagnostic and therapeutic protocols. Personalized motion modeling required patient-specific four-dimensional (4D) imaging which in the case of 4D computed tomography (4D CT) acquisition is associated with an increased dose. The goal of this work was to develop a global respiratory motion model capable of relating external patient surface motion to internal structure motion without the need for a patient-specific 4D CT acquisition. The proposed global model is based on principal component analysis and can be adjusted to a given patient anatomy using only one or two static CT images in conjunction with a respiratory synchronized patient external surface motion. It is based on the relation between the internal motion described using deformation fields obtained by registering 4D CT images and patient surface maps obtained either from optical imaging devices or extracted from CT image-based patient skin segmentation. 4D CT imag...Continue Reading

References

Oct 6, 1999·American Journal of Respiratory and Critical Care Medicine·H A TiddensJ C de Jongste
Sep 6, 2005·International Journal of Radiation Oncology, Biology, Physics·Daniel A LowJeffrey D Bradley
Oct 7, 2006·Medical Physics·Jamie R McClellandDavid J Hawkes
Dec 13, 2007·Medical Physics·Tinsu PanDershan Luo
Jul 22, 2008·International Journal of Radiation Oncology, Biology, Physics·Yelin SuhPaul J Keall
Oct 2, 2008·Physics in Medicine and Biology·R ColganS Webb
Jul 5, 2012·Medical Physics·Hadi FayadDimitris Visvikis
Nov 6, 2012·Medical Image Analysis·J R McClellandA P King

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