A 5-day antibiotic course for treatment of intermittent catheter-associated urinary tract infection in patients with spinal cord injury

Spinal Cord Series and Cases
Jean-Gabriel PrevinaireJean-Marc Soler

Abstract

This was a retrospective monocentric study conducted at Centre Calvé, France, with the objective of evaluating the effectiveness of a 5-day course of antibiotics for symptomatic (mild urinary tract infection, UTI) or asymptomatic (aBact) bacteriuria in patients with spinal cord injury on intermittent catheterization. This study was conducted from May 2013 to September 2016. Antibiotic selection always followed culture collection and analysis of antibiograms. Patients with febrile UTI (>38°5) or recent history of urolithiasis were excluded. Fifty-seven patients underwent 111 5-day courses of antibiotics. The two main bacteria involved were Escherichia coli and Klebsiella Pneumoniae. Most commonly prescribed antibiotics were cephalosporins, cotrimoxazole, fluoroquinolones and nitrofurantoins. On day 4 of the antibiotic course, bacteria were eradicated in 99% of cases. Clinical cure occurred in all patients by day 5 (end of treatment). After treatment, recurrence of UTI occurred in 16% of patients at week 3, 38% at week 6 and 50% at week 9. This rate was not significantly different from patients initially treated for aBact (20%, 35% and 44%, respectively). The UTI-free period was significantly shorter after treatment for aBact (45...Continue Reading

References

Dec 1, 1990·The Journal of Antimicrobial Chemotherapy·A J StannardG S Tillotson
Mar 1, 1995·Archives of Physical Medicine and Rehabilitation·D D Cardenas, T M Hooton
Jan 10, 2002·Archives of Physical Medicine and Rehabilitation·Sally C MortonBarbara G Vickrey
May 28, 2004·The Journal of Spinal Cord Medicine·Jeanne M HoffmanDiana D Cardenas
Sep 10, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Gordon DowLindsay E Nicolle
Sep 10, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kalpana Gupta, Thomas M Hooton
Feb 17, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lindsay E NicolleUNKNOWN American Geriatric Society
Jul 11, 2006·International Journal of Antimicrobial Agents·Lindsay E Nicolle
Oct 9, 2009·Acta Clinica Belgica·K EveraertM van Driel
Feb 23, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas M HootonUNKNOWN Infectious Diseases Society of America
Dec 7, 2010·Neurorehabilitation and Neural Repair·Esthel RoncoJean-Louis Gaillard
Dec 20, 2011·The Journal of Urology·Anne P CameronKatherine G Schomer
Apr 17, 2016·BMC Infectious Diseases·Aurélien DinhLouis Bernard

❮ Previous
Next ❯

Citations

Feb 21, 2019·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Marcello Torres da SilvaPaulo Sergio Siebra Beraldo
Mar 3, 2020·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Sandra EngbergMikel Gray

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

International Journal of Urology : Official Journal of the Japanese Urological Association
Narihito SekiSeiji Naito
The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases
Ana Claudia ParadellaCarlos Brites
Archives of Physical Medicine and Rehabilitation
W H DonovanM R Clowers
Archives of Disease in Childhood
T NolanF Oberklaid
© 2022 Meta ULC. All rights reserved