Abstract
This was a retrospective monocentric study conducted at Centre Calvé, France, with the objective of evaluating the effectiveness of a 5-day course of antibiotics for symptomatic (mild urinary tract infection, UTI) or asymptomatic (aBact) bacteriuria in patients with spinal cord injury on intermittent catheterization. This study was conducted from May 2013 to September 2016. Antibiotic selection always followed culture collection and analysis of antibiograms. Patients with febrile UTI (>38°5) or recent history of urolithiasis were excluded. Fifty-seven patients underwent 111 5-day courses of antibiotics. The two main bacteria involved were Escherichia coli and Klebsiella Pneumoniae. Most commonly prescribed antibiotics were cephalosporins, cotrimoxazole, fluoroquinolones and nitrofurantoins. On day 4 of the antibiotic course, bacteria were eradicated in 99% of cases. Clinical cure occurred in all patients by day 5 (end of treatment). After treatment, recurrence of UTI occurred in 16% of patients at week 3, 38% at week 6 and 50% at week 9. This rate was not significantly different from patients initially treated for aBact (20%, 35% and 44%, respectively). The UTI-free period was significantly shorter after treatment for aBact (45...Continue Reading
References
Dec 1, 1990·The Journal of Antimicrobial Chemotherapy·A J StannardG S Tillotson
Aug 1, 1987·The Journal of Urology·J L MohlerR C Flanigan
Nov 1, 1984·The Journal of Urology·F M Maynard, A C Diokno
Mar 1, 1995·Archives of Physical Medicine and Rehabilitation·D D Cardenas, T M Hooton
Jan 10, 2002·Archives of Physical Medicine and Rehabilitation·Sally C MortonBarbara G Vickrey
Aug 20, 2002·Spinal Cord·J J Wyndaele
May 28, 2004·The Journal of Spinal Cord Medicine·Jeanne M HoffmanDiana D Cardenas
Sep 10, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Gordon DowLindsay E Nicolle
Sep 10, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kalpana Gupta, Thomas M Hooton
Feb 17, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lindsay E NicolleUNKNOWN American Geriatric Society
Jul 11, 2006·International Journal of Antimicrobial Agents·Lindsay E Nicolle
Oct 9, 2009·Acta Clinica Belgica·K EveraertM van Driel
Feb 23, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas M HootonUNKNOWN Infectious Diseases Society of America
Dec 7, 2010·Neurorehabilitation and Neural Repair·Esthel RoncoJean-Louis Gaillard
Dec 20, 2011·The Journal of Urology·Anne P CameronKatherine G Schomer
Sep 12, 2012·Spinal Cord·R BöthigS Hirschfeld
Sep 17, 2013·Archives of Physical Medicine and Rehabilitation·Rabih O DarouicheCharles G Minard
Feb 12, 2014·Spinal Cord·S B YoonZ A Han
Dec 15, 2015·World Journal of Urology·Zafer TandoğduFlorian Wagenlehner
Apr 17, 2016·BMC Infectious Diseases·Aurélien DinhLouis Bernard
Jun 1, 2016·Médecine et maladies infectieuses·L WeglinskiA Dinh
Citations
Feb 21, 2019·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Marcello Torres da SilvaPaulo Sergio Siebra Beraldo
Mar 3, 2020·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Sandra EngbergMikel Gray
Nov 26, 2019·Porto Biomedical Journal·Daniela M AmaralMarta S R Torres
Aug 19, 2021·European Urology Focus·Andrea M SartoriJürgen Pannek