[A 68-year-old patient with atrial flutter/fibrillation, inadequate anticoagulation, subacute amaurosis, normal ESR, and lymphadenopathy].

Der Internist
T N AbahjiH J Anders

Abstract

We present a rare manifestation of chronic lymphatic leukemia with progressive bilateral visual loss and the typical fundoscopic picture of anterior ischemic optic nerve neuropathy (AION). Clinical symptoms were due to meningeal metastases and tumor cell infiltration of the optic nerve. The diagnostic clue was provided by lumbar puncture with pressure measurement, which made it possible to differentiate AION from papillitis and papilledema. In this case the patient was able to regain his initial visual activity after intrathecal and systemic polychemotherapy.

References

Dec 1, 1975·Brain : a Journal of Neurology·D R Boghen, J S Glaser
Dec 1, 1974·The British Journal of Ophthalmology·S S Hayreh
Oct 1, 1996·American Journal of Ophthalmology·A C ArnoldJ M Alexander
Jan 14, 1999·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·S S HayrehM B Zimmerman
Jun 30, 2000·Seminars in Neurology·V A Purvin
Sep 5, 2002·American Journal of Ophthalmology·Nancy J NewmanUNKNOWN Ischemic Optic Neuropathy Decompression Trial Research Group
Jun 5, 2003·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Anthony C Arnold

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