A 75-kD autoantigen recognized by sera from patients with X-linked autoimmune enteropathy associated with nephropathy

Clinical and Experimental Immunology
Ichiro KobayashiN Ishikawa

Abstract

Autoimmune enteropathy (AIE) is a rare disorder characterized by intractable diarrhoea and antienterocyte autoantibody. In this study, we detected a 75-kD autoantigen which distributed through the whole intestine and the kidney, as assessed by Western blot analysis using sera from two unrelated cases of AIE associated with nephropathy. Our results suggest that the detection of the autoantibody against the 75-kD antigen has a diagnostic value in AIE and that the autoimmune reaction against the 75-kD antigen may be implicated in the development of intestinal and renal tissue damage in this rare disorder.

References

Jun 1, 1991·The Journal of Pediatrics·R B CollettiH S Winter
Apr 1, 1989·Journal of Pediatric Gastroenterology and Nutrition·S G MittonJ A Walker-Smith
Nov 1, 1986·British Medical Journal·R MirakianG F Bottazzo
Apr 1, 1988·The Journal of Clinical Endocrinology and Metabolism·M E FisfalenK Soltani
Jun 1, 1985·Journal of Pediatric Gastroenterology and Nutrition·D J Unsworth, J A Walker-Smith
May 1, 1982·The Journal of Pediatrics·B R PowellP Stenzel
Apr 1, 1982·American Journal of Diseases of Children·D EllisR Jaffe
Jul 1, 1995·European Journal of Pediatrics·A Ventura, D Dragovich
Oct 1, 1995·Human Pathology·L MooreA Ferrante
May 3, 1996·Cell·R Tisch, H McDevitt
Jul 1, 1996·Gastroenterology·A BousvarosA E Mulberg

❮ Previous
Next ❯

Citations

Jul 20, 2012·Current Gastroenterology Reports·Nicole M GentileDarrell S Pardi
Jul 17, 2007·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Asha MoudgilNaynesh Kamani
Oct 6, 2007·Immunologic Research·Hans D OchsTroy R Torgerson
Dec 3, 2014·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Natsuko ChidaTadashi Ariga
Sep 7, 2013·Advances in Pediatrics·Pierre Russo
Sep 1, 2010·Surgical Pathology Clinics·Pierre Russo
Nov 17, 2009·Allergologia et immunopathologia·A Blanco QuirósJ A Garrote Adrados
Jul 28, 2015·Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology·Natsuko Chida, Ichiro Kobayashi
Oct 13, 2007·The Journal of Allergy and Clinical Immunology·Troy R Torgerson, Hans D Ochs
Jan 22, 2005·Immunological Reviews·Hans D OchsTroy R Torgerson
Oct 27, 2015·Current Allergy and Asthma Reports·Monica G Lawrence
Apr 14, 2016·Journal of Clinical Immunology·Anne Depince-BergerStephane Paul
Aug 5, 1998·Lancet·R MirakianG F Bottazzo
Feb 27, 2016·Annals of the New York Academy of Sciences·Rosa BacchettaMaria-Grazia Roncarolo
Sep 8, 2010·Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology·Keisuke OtsuboToshio Miyawaki
Feb 11, 2005·Current Opinion in Gastroenterology·Frank M RuemmeleOlivier Goulet
May 18, 2017·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Daniel TegtmeyerChristian Klemann
Aug 17, 2004·The American Journal of Gastroenterology·Francisco LeónGarbiñe Roy
Sep 30, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Natacha Patey-Mariaud de SerreNicole Brousse
Nov 9, 2007·Current Opinion in Allergy and Clinical Immunology·Troy R Torgerson, Hans D Ochs
Apr 5, 2000·Journal of Pediatric Gastroenterology and Nutrition·N C Pirisi-HauckS Kurunczi
Dec 17, 2003·Journal of Pediatric Gastroenterology and Nutrition·Philip M ShermanErnest Cutz
Aug 25, 2020·Digestive Diseases and Sciences·Charles B ChenKadakkal Radhakrishnan
Jul 9, 2008·Scandinavian Journal of Gastroenterology·Lars M MarthinsenJan Ejderhamn
Jun 13, 2017·Frontiers in Immunology·Leonn Mendes Soares PereiraAntonio Carlos Rosário Vallinoto
Oct 20, 2018·Journal of Cell Science·Thaher Pelaseyed, Anthony Bretscher
Mar 4, 2009·Scandinavian Journal of Gastroenterology·Massimo MontaltoGiovanni Gasbarrini
Mar 12, 2021·Frontiers in Pediatrics·Federica Barzaghi, Laura Passerini

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
Pierre A RussoC C Roy
Clinical Immunology : the Official Journal of the Clinical Immunology Society
Ichiro KobayashiT Ariga
© 2022 Meta ULC. All rights reserved