A Bayesian evaluation of three diagnostic assays for the detection of Giardia duodenalis in symptomatic and asymptomatic dogs

Veterinary Parasitology
T GeurdenE Claerebout

Abstract

A Bayesian approach was used to evaluate three commonly used diagnostic assays for the detection of Giardia duodenalis in dogs: microscopical examination (ME), a commercial immunofluorescence assay (IFA: MerifluorGiardia test) and a commercial immunochromatographic assay (SNAP: Idexx SNAPGiardia test). These assays were evaluated for use in two different settings: in a cross-sectional epidemiological survey in household dogs and in a clinical survey, both conducted in the northern part of Belgium. A total of 272 faecal samples from household dogs and 141 faecal samples from clinically affected dogs were examined using these three diagnostic assays. The Bayesian analysis indicated that all tests were highly specific (specificity above 90%), and that the IFA is more sensitive than SNAP and ME, both in an epidemiological and in a clinical setting. For all three tests, the estimated sensitivity values were higher in the clinical compared to the epidemiological survey, whereas the specificity values were comparable in both studies. The results of the present study indicate that IFA is a highly specific and sensitive technique for the detection of G. duodenalis cysts, both for use in an epidemiological or clinical survey. The SNAP is...Continue Reading

References

Sep 1, 1980·Australian Veterinary Journal·A D Watson
Jan 1, 1993·Transactions of the Royal Society of Tropical Medicine and Hygiene·R M HopkinsR C Thompson
May 18, 1999·The Veterinary Journal·R J BuggR C Thompson
Apr 3, 2003·Parasite : Journal De La Société Française De Parasitologie·C DecockM Franc
Aug 21, 2003·Parasitology Research·D Barutzki, R Schaper
Mar 3, 2005·Veterinary Parasitology·R PapiniG Cardini
Feb 16, 2006·Epidemiology·Dirk BerkvensEmmanuel Lesaffre

❮ Previous
Next ❯

Citations

Jan 14, 2012·Veterinary Parasitology·Ruth FiechterManuela Schnyder
Jul 19, 2011·Parasitology International·Aleksandro S Da SilvaSilvia G Monteiro
Apr 14, 2011·The Veterinary Clinics of North America. Small Animal Practice·Nora Berghoff, Jörg M Steiner
Jul 20, 2010·Veterinary Parasitology·C EpeL Kreienbrock
Mar 6, 2010·Trends in Parasitology·Lora R BallweberVitaliano A Cama
Nov 26, 2009·The Veterinary Clinics of North America. Small Animal Practice·Patricia A Payne, Marjory Artzer
Aug 28, 2009·Veterinary Parasitology·Maureen C Gates, Thomas J Nolan
Mar 17, 2009·Experimental Parasitology·Thomas GeurdenEdwin Claerebout
Jan 22, 2009·Veterinary Parasitology·E ClaereboutT Geurden
Aug 7, 2013·The Journal of Small Animal Practice·S DupontS Daminet
Nov 6, 2013·Biotechnology Advances·Anson V KoehlerRobin B Gasser
Sep 9, 2011·Veterinary Parasitology·Viorica MirceanVasile Cozma
Mar 22, 2015·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Juan David RamírezMyriam Consuelo Lopez
Aug 19, 2011·Veterinary Parasitology·Andrea V ScorzaMichael R Lappin
Jun 3, 2016·The Journal of Small Animal Practice·M CostaK Papasouliotis
Sep 2, 2016·Journal of the American Veterinary Medical Association·Meriam N SalehAnne M Zajac
Dec 9, 2016·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Alison E HillmanR C Andrew Thompson
Apr 23, 2013·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Roberto PapiniAnnunziata Giangaspero
Jul 30, 2017·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Meriam N SalehAnne M Zajac
Aug 2, 2018·Parasites & Vectors·Mathilde UiterwijkHarm W Ploeger
Apr 15, 2019·Journal of Veterinary Internal Medicine·Meriam N SalehAnne M Zajac
Aug 3, 2018·Parasites & Vectors·Jennifer Mizhquiri BarbechoJanice L Liotta
Apr 15, 2016·Acta Parasitologica·João Alves, Ana Santos
Apr 12, 2018·Anais Da Academia Brasileira De Ciências·Viviane A N CostaAdriana P Sudré
Sep 4, 2019·The Onderstepoort Journal of Veterinary Research·Regina D MiamboSamson Mukaratirwa
Oct 12, 2020·Tropical Animal Health and Production·Md Aminul IslamAkm Anisur Rahman
Oct 12, 2020·Acta Parasitologica·Agnieszka Piekara-StępińskaJacek Bania
Nov 4, 2020·Parasites & Vectors·Isaia SymeonidouElias Papadopoulos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.