A Bayesian model comparison approach to test the specificity of visual integration impairment in schizophrenia or psychosis

Psychiatry Research
Tyler B GroveIvy F Tso

Abstract

Impaired visual integration is well documented in schizophrenia and related to functional outcomes. However, it is unclear if this deficit is specific to schizophrenia, or characteristic of psychosis more broadly. To address this question, this study used a Bayesian model comparison approach to examine the evidence of three grouping models of visual integration performance in 116 individuals with schizophrenia (SZ), schizoaffective disorder (SA), bipolar disorder (BD) with or without a history of prominent psychosis (BDP+ and BDP-, respectively), or no psychiatric diagnosis (healthy controls; HC). We compared: (1) Psychosis Model (psychosis, non-psychosis), where the psychosis group included SZ, SA, and BDP+, and the non-psychosis group included BDP- and HC; (2) Schizophrenia Model (SZ, non-SZ); and (3) DSM Model (SZ, SA, BD, HC). The relationship between visual integration and general cognition was also explored. The Psychosis Model showed the strongest evidence, and visual integration was associated with general cognition in participants with psychosis. The results were consistent with the Research Domain Criteria (RDoC) framework, indicating that visual integration impairment is characteristic of psychosis and not specific t...Continue Reading

References

Nov 1, 1978·The British Journal of Psychiatry : the Journal of Mental Science·R C YoungD A Meyer
Oct 5, 2001·Nature Reviews. Neuroscience·A K EngelW Singer
Jun 26, 2003·The Journal of Clinical Psychiatry·Scott W Woods
Aug 19, 2003·Comprehensive Psychiatry·Paul E KeckRobert M Post
Aug 5, 2004·Neuropsychology·Szabolcs KériZoltán Janka
Dec 21, 2004·Vision Research·Sunita Mandon, Andreas K Kreiter
Mar 16, 2006·Cognitive Neuropsychiatry·Steven M SilversteinAdam Savitz
Aug 4, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Peter J UhlhaasEugenio Rodriguez
Apr 3, 2007·Experimental Brain Research·Elisa CiaramelliElisabetta Ladavas
Jun 14, 2008·Biological Psychiatry·Pamela D ButlerSteven C Dakin
Jul 21, 2009·Journal of Integrative Neuroscience·Steven M SilversteinDeborah M Little
Jul 3, 2010·The American Journal of Psychiatry·Thomas InselPhilip Wang
Oct 25, 2011·Schizophrenia Bulletin·Steven M SilversteinMilton E Strauss
Jan 19, 2012·Journal of Abnormal Psychology·Ivy F TsoPatricia J Deldin
Aug 14, 2012·British Journal of Clinical Pharmacology·Malcolm Lader
Mar 23, 2013·Frontiers in Psychology·Pamela D ButlerPejman Sehatpour
Apr 19, 2013·Nature Reviews. Neuroscience·Charles D Gilbert, Wu Li
May 15, 2013·Schizophrenia Bulletin·Ivy F TsoPatricia J Deldin
Jul 3, 2013·Schizophrenia Bulletin·Milton E StraussSteven M Silverstein
Sep 17, 2013·Cognitive, Affective & Behavioral Neuroscience·Julia M SheffieldDeanna M Barch
Oct 25, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Stephan F TaylorRobert C Welsh
Apr 2, 2014·Schizophrenia Bulletin·Godfrey D Pearlson, Judith M Ford
Apr 2, 2014·The American Journal of Psychiatry·Thomas R Insel
Nov 21, 2014·Journal of Neurophysiology·Niels A KloostermanTobias H Donner
Jan 13, 2015·Annual Review of Clinical Psychology·Godfrey D Pearlson
Mar 6, 2015·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Mei-Hua HallJordan W Smoller
Jul 15, 2015·Neuropsychologia·Steven M SilversteinDeanna M Barch
Jul 18, 2015·Psychiatry Research·Steven M SilversteinSabine Wilhelm
Sep 14, 2015·Schizophrenia Research·Ivy F TsoStephan F Taylor

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.