A bioactive seco-rosane diterpenoid from Vellozia candida

Journal of Natural Products
L M ValenteA C Pinto

Abstract

Bioassay-directed fractionation of the bioactive alcoholic extracts of Vellozia candida yielded a new 6,7-seco-rosane diterpenoid, candidalactone (1), which showed moderate toxicity toward DNA repair-deficient mutants of Saccharomyces cerevisiae. Another new but inactive rosane diterpenoid, candidenodiol (3), was also obtained.

Citations

Sep 26, 2009·The Journal of Organic Chemistry·James R Green, Andy A Tjeng

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