A biocatalytic redox isomerisation

Chemical Communications : Chem Comm
Serena GargiuloFrank Hollmann

Abstract

A bi-enzymatic cascade for the redox-isomerisation of allylic alcohol is presented. Coupling of an alcohol dehydrogenase to an enoate reductase has been successfully applied in one pot for the isomerisation of an allylic alcohol to the corresponding ketone. Critical parameters for yield and selectivity have been investigated.

References

Sep 6, 2001·Biomolecular Engineering·B BoonstraN C Bruce
Apr 6, 2004·Current Opinion in Chemical Biology·Wolfgang KroutilKurt Faber
Mar 14, 2007·Current Opinion in Chemical Biology·Rainer StuermerKurt Faber
Feb 12, 2008·Journal of Bacteriology·Diederik Johannes OppermanEsta van Heerden
Aug 16, 2008·Applied Microbiology and Biotechnology·Volker HöllriglAndreas Schmid
Nov 28, 2009·Chembiochem : a European Journal of Chemical Biology·Björn V AdalbjörnssonNigel S Scrutton
Feb 9, 2010·Biochemical and Biophysical Research Communications·Diederik J OppermanEsta van Heerden
Dec 7, 2010·Current Opinion in Chemical Biology·Joerg H SchrittwieserWolfgang Kroutil
Jan 5, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·Nanna AhlstenBelén Martín-Matute

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Citations

Dec 24, 2013·Applied Microbiology and Biotechnology·Selin KaraMarion B Ansorge-Schumacher
Jan 5, 2016·Journal of the American Chemical Society·Tanja KnausNigel S Scrutton
Aug 24, 2016·Journal of the American Chemical Society·Alexander GeddesNigel S Scrutton
Feb 13, 2014·Angewandte Chemie·Bettina M NestlBernhard Hauer
Jul 10, 2018·Angewandte Chemie·Yu-Chang LiuJan Deska
Nov 2, 2019·Chemical Society Reviews·Erika Tassano, Mélanie Hall
May 12, 2020·Chemical Communications : Chem Comm·Erika TassanoMélanie Hall
Jan 24, 2013·Chemistry : a European Journal·Katharina TauberWolfgang Kroutil
Apr 3, 2016·Chembiochem : a European Journal of Chemical Biology·Sabrina ReichBernhard Hauer
Apr 25, 2020·Angewandte Chemie·Frank HollmannCaroline E Paul
May 10, 2017·Chemical Reviews·Joerg H SchrittwieserWolfgang Kroutil

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