A Biphasic Change of Regional Blood Volume in the Frontal Cortex during Non-Rapid Eye Movement Sleep: A Near-Infrared Spectroscopy Study

Sleep
Zhongxing Zhang, Ramin Khatami

Abstract

Current knowledge on hemodynamics in sleep is limited because available techniques do not allow continuous recordings and mainly focus on cerebral blood flow while neglecting other important parameters, such as blood volume (BV) and vasomotor activity. Observational study. Continuous measures of hemodynamics over the left forehead and biceps were performed using near-infrared spectroscopy (NIRS) during nocturnal polysomnography in 16 healthy participants in sleep laboratory. Temporal dynamics and mean values of cerebral and muscular oxygenated hemoglobin (HbO2), deoxygenated hemoglobin (HHb), and BV during different sleep stages were compared. A biphasic change of cerebral BV was observed which contrasted a monotonic increase of muscular BV during non-rapid eye movement sleep. A significant decrement in cerebral HbO2 and BV accompanied by an increase of HHb was recorded at sleep onset (Phase I). Prior to slow wave sleep (SWS) HbO2 and BV turned to increase whereas HHb began to decrease in subsequent Phase II suggested increased brain perfusion during SWS. The cerebral HbO2 slope correlated to BV slope in Phase I and II, but it only correlated to HHb slope in Phase II. The occurrence time of inflection points correlated to SWS l...Continue Reading

References

Dec 1, 1992·Journal of Applied Physiology·J TrinderP Wilkin
May 1, 1995·Clinical Neurology and Neurosurgery·J KlingelhöferB Conrad
Jul 1, 1997·Brain : a Journal of Neurology·A R BraunP Herscovitch
Mar 11, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·K KräuchiA Wirz-Justice
Jun 11, 2003·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Hiroshi ItoShuichi Miura
Jun 9, 2004·Nature·Reto HuberGiulio Tononi
Jun 15, 2004·Journal of Applied Physiology·Guy E MeadowsDouglas R Corfield
Dec 27, 2005·Sleep Medicine Reviews·Giulio Tononi, Chiara Cirelli
Aug 1, 2006·Progress in Brain Research·Eus J W Van Someren
Oct 30, 2007·Nature Neuroscience·Costantino Iadecola, Maiken Nedergaard
Jan 15, 2008·Brain : a Journal of Neurology·Roy J E M RaymannEus J W Van Someren
Sep 26, 2008·Proceedings of the National Academy of Sciences of the United States of America·Thien Thanh Dang-VuPierre Maquet
Nov 6, 2008·Nature Reviews. Neuroscience·James M KruegerJaak Panksepp
Sep 10, 2011·Neuron·Gabor C Petzold, Venkatesh N Murthy
Apr 13, 2012·The Journal of Physiology·C K WillieP N Ainslie
Jun 14, 2012·Stroke; a Journal of Cerebral Circulation·Fabio PizzaClaudio L Bassetti
Jul 25, 2012·The Journal of Physiology·Jill N Barnes
May 3, 2013·Nature Reviews. Neuroscience·Vladyslav V Vyazovskiy, Kenneth D Harris
May 9, 2013·The European Journal of Neuroscience·James M KruegerDaniel J Buysse
Oct 19, 2013·Science·Lulu XieMaiken Nedergaard
Nov 6, 2013·Proceedings of the National Academy of Sciences of the United States of America·Stephen R MorairtyThomas S Kilduff
Aug 27, 2014·The European Journal of Neuroscience·Zhongxing Zhang, Ramin Khatami
Aug 28, 2014·Journal of Sleep Research·Rositsa PoryazovaClaudio L Bassetti

❮ Previous
Next ❯

Citations

Apr 6, 2016·Frontiers in Neuroscience·Giovanni PellegrinoChristophe Grova
Aug 29, 2016·Sleep Medicine Reviews·Chamara V SenaratnaShyamali C Dharmage
Feb 16, 2017·Neurorehabilitation and Neural Repair·Vera GramignaAldo Quattrone
Jun 4, 2019·Frontiers in Human Neuroscience·Adile OnizMurat Ozgoren
Dec 18, 2020·Frontiers in Neurology·Haoran RenWei Chen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Vaginosis

Bacterial vaginosis can increase the risk of sexually transmitted infections and in rare cases lead to pelvic inflammatory diseases. Discover the latest research on Bacterial Vaginosis here.