PMID: 15219159Jun 29, 2004Paper

A blocking Gibbs sampling method to detect major genes with phenotypic data from a diallel mating

Genetical Research
Wen ZengBailian Li

Abstract

Diallel mating is a frequently used design for estimating the additive and dominance genetic (polygenic) effects involved in quantitative traits observed in the half- and full-sib progenies generated in plant breeding programmes. Gibbs sampling has been used for making statistical inferences for a mixed-inheritance model (MIM) that includes both major genes and polygenes. However, using this approach it has not been possible to incorporate the genetic properties of major genes with the additive and dominance polygenic effects in a diallel mating population. A parent block Gibbs sampling method was developed in this study to make statistical inferences about the major gene and polygenic effects on quantitative traits for progenies derived from a half-diallel mating design. Using simulated data sets with different major and polygenic effects, the proposed method accurately estimated the major and polygenic effects of quantitative traits, and possible genotypes of parents and progenies. The impact of specifying different prior distributions was examined and was found to have little effect on inference on the posterior distribution. This approach was applied to an experimental data set of Loblolly pine (Pinus taeda L.) derived from...Continue Reading

Citations

Mar 18, 2006·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Patrik Waldmann, Tore Ericsson
Aug 10, 2006·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Hua LiBailian Li

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