A breast/ovarian cancer patient with germline mutations in both BRCA1 and BRCA2

May 18, 2007·Journal of Genetic Counseling·Janice L BerlinerUNKNOWN Practice Issues Subcommittee of the National Society of Genetic Counselors' Familial Cancer Risk Counseling Special Interest

Co-segregation of BRCA1 185delAG mutation and BRCA2 6174delT in one single family

Feb 21, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R Gershoni-BaruchG Freid

Loss of heterozygosity in bilateral breast cancer

Feb 24, 2001·Breast Cancer Research and Treatment·J KolliasJ D Brook

An unaffected individual from a breast/ovarian cancer family with germline mutations in both BRCA1 and BRCA2

Mar 25, 2000·Clinical Genetics·R MoslehiS Narod

Hereditary Breast Cancer: Risk Assessment Is the Easy Part

May 12, 2001·The Breast Journal·Patricia T. Kelly

Deleterious mutations of both BRCA1 and BRCA2 in three siblings

Aug 28, 1999·Genetic Testing·S Loader, P T Rowley

Double heterozygotes for non-Caucasian families with mutations in BRCA-1 and BRCA-2 genes

May 11, 2006·The Breast Journal·Doo Ho ChoiBruce G Haffty

The genetics of breast cancer susceptibility

Feb 3, 1999·Annual Review of Genetics·N Rahman, M R Stratton

Expression profiles of BRCA1 splice variants in asynchronous and in G1/S synchronized tumor cell lines

Feb 13, 2001·Biochemical and Biophysical Research Communications·T I Orban, E Olah

Hereditary breast/ovarian cancer--pitfalls in genetic counseling

Oct 31, 2001·Clinical Genetics·E Dagan, R Gershoni-Baruch

Molecular and genealogical characterization of the R1443X BRCA1 mutation in high-risk French-Canadian breast/ovarian cancer families

May 11, 2005·Human Genetics·Hélène VézinaJacques Simard

Coincident PTCH and BRCA1 germline mutations in a patient with nevoid basal cell carcinoma syndrome and familial breast cancer

Mar 7, 2001·The Journal of Investigative Dermatology·J ReifenbergerA Hauschild

Deletions removing the last exon of TACSTD1 constitute a distinct class of mutations predisposing to Lynch syndrome

Jan 30, 2009·Human Mutation·Marietta E KovacsEdith Olah

A case of familial breast cancer with double heterozygosity for BRCA1 and BRCA2 genes

Dec 18, 2012·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Tadashi NomizuYoshiko Yamaguchi

Male breast cancer: is the scenario changing.

Jun 19, 2008·World Journal of Surgical Oncology·Kaiyumars B ContractorHemant Singhal

De novo BRCA1 mutation in a patient with breast cancer and an inherited BRCA2 mutation

Jul 27, 1999·American Journal of Human Genetics·A TesorieroD Venter

Double heterozygotes for the Ashkenazi founder mutations in BRCA1 and BRCA2 genes

Oct 3, 1998·American Journal of Human Genetics·E FriedmanA D Abeliovich

A breast cancer patient of Scottish descent with germ-line mutations in BRCA1 and BRCA2

Jun 19, 1998·American Journal of Human Genetics·A LiedeS A Narod

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

Apr 5, 2003·American Journal of Human Genetics·A AntoniouD F Easton

Large genomic BRCA2 rearrangements and male breast cancer

Nov 23, 2006·Cancer Detection and Prevention·Ritva KarhuKirsi Syrjäkoski

Concomitant BRCA1 and BRCA2 gene mutations in an Ashkenazi Jewish woman with primary breast and ovarian cancer

Apr 4, 2007·American Journal of Obstetrics and Gynecology·Whitney A SpannuthAnil K Sood

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

Nov 12, 2016·Breast Cancer Research : BCR·Timothy R RebbeckSusan J Ramus

Incidence of BRCA1 and BRCA2 mutations in young Korean breast cancer patients

May 1, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Doo Ho ChoiBruce G Haffty

BRCA2-null embryonic survival is prolonged on the BALB/c genetic background

Aug 15, 2000·Molecular Carcinogenesis·L M BennettR W Wiseman

Double Heterozygosity for BRCA1 Pathogenic Variant and BRCA2 Polymorphic Stop Codon K3326X: A Case Report in a Southern Italian Family

Jan 19, 2018·International Journal of Molecular Sciences·Raffaele PalmirottaFranco Silvestris

A cautionary note: false homozygosity for BRCA2 6174delT mutation resulting from a single nucleotide polymorphism masking the wt allele

Jun 25, 2002·European Journal of Human Genetics : EJHG·Angela R SolanoErnesto J Podesta

Caucasian family with two independent mutations: 2594delC in BRCA1 and 5392delAG in BRCA2 gene

Jun 8, 2001·American Journal of Medical Genetics·A GangulyT Ganguly

Presymptomatic breast cancer in Egypt: role of BRCA1 and BRCA2 tumor suppressor genes mutations detection.

Jun 29, 2010·Journal of Experimental & Clinical Cancer Research : CR·Safinaz S IbrahimMervat M Hashishe

The current social, political, and medical role of genetic testing in familial breast and ovarian carcinomas

Feb 27, 1999·Current Opinion in Obstetrics & Gynecology·J N Weitzel

Ethnic differences in cancer risk resulting from genetic variation

Jan 12, 2000·Cancer·S L Neuhausen

Prevalence of founder BRCA1 and BRCA2 mutations among breast and ovarian cancer patients in Hungary

May 8, 2000·International Journal of Cancer. Journal International Du Cancer·M Van Der LooijE Olah

Retinoblastoma and hypochondroplasia: a case report of two germline mutations arising simultaneously

Jul 16, 2005·Ophthalmic Genetics·Tony TsaiArpitha Muthialu

Hereditary breast cancer; Genetic penetrance and current status with BRCA

Dec 16, 2018·Journal of Cellular Physiology·Morteza MahdaviVinod Gopalan

A family with three germline mutations in BRCA1 and BRCA2

Oct 27, 1998·Clinical Genetics·A LiedeR Moslehi

Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations.

Feb 16, 2018·Human Mutation·Timothy R RebbeckKatherine L Nathanson

Literature Review of BARD1 as a Cancer Predisposing Gene with a Focus on Breast and Ovarian Cancers.

Jul 31, 2020·Genes·Wejdan M AleneziPatricia N Tonin

Five Italian Families with Two Mutations in BRCA Genes.

Dec 9, 2020·Genes·Maria Teresa VietriAnna Maria Molinari

Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination.

Oct 13, 2021·NPJ Breast Cancer·Jeremy SettonDiana Mandelker

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

May 15, 1997·Genes & Development·T LudwigA Efstratiadis

❮ Previous

Next ❯

Related Concepts

Related Feeds

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.

Breast Cancer: BRCA1 & BRCA2

Mutations involving BRCA1, found on chromosome 17, and BRCA2, found on chromosome 13, increase the risk for specific cancers, such as breast cancer. Discover the last research on breast cancer BRCA1 and BRCA2 here.

A breast/ovarian cancer patient with germline mutations in both BRCA1 and BRCA2

Abstract

References

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

The carrier frequency of the BRCA1 185delAG mutation is approximately 1 percent in Ashkenazi Jewish individuals

Linkage analysis of 26 Canadian breast and breast-ovarian cancer families

BRCA1 mutations in primary breast and ovarian carcinomas

Identification of the breast cancer susceptibility gene BRCA2

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

BRCA2 germline mutations in male breast cancer cases and breast cancer families

Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer

Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13

Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2

The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%

Citations

A breast cancer patient from Italy with germline mutations in both the BRCA1 and BRCA2 genes

Four new cases of double heterozygosity for BRCA1 and BRCA2 gene mutations: clinical, pathological, and family characteristics

Two patients with germline mutations in both BRCA1 and BRCA2 discovered unintentionally: a case series and discussion of BRCA testing modalities

BRCA1, BRCA2, TP53, and CDKN2A germline mutations in patients with breast cancer and cutaneous melanoma

Risk assessment and genetic counseling for hereditary breast and ovarian cancer: recommendations of the National Society of Genetic Counselors

Co-segregation of BRCA1 185delAG mutation and BRCA2 6174delT in one single family

Loss of heterozygosity in bilateral breast cancer

An unaffected individual from a breast/ovarian cancer family with germline mutations in both BRCA1 and BRCA2

Hereditary Breast Cancer: Risk Assessment Is the Easy Part

Deleterious mutations of both BRCA1 and BRCA2 in three siblings

Double heterozygotes for non-Caucasian families with mutations in BRCA-1 and BRCA-2 genes

The genetics of breast cancer susceptibility

Expression profiles of BRCA1 splice variants in asynchronous and in G1/S synchronized tumor cell lines

Hereditary breast/ovarian cancer--pitfalls in genetic counseling

Molecular and genealogical characterization of the R1443X BRCA1 mutation in high-risk French-Canadian breast/ovarian cancer families

Coincident PTCH and BRCA1 germline mutations in a patient with nevoid basal cell carcinoma syndrome and familial breast cancer

Deletions removing the last exon of TACSTD1 constitute a distinct class of mutations predisposing to Lynch syndrome

A case of familial breast cancer with double heterozygosity for BRCA1 and BRCA2 genes

Male breast cancer: is the scenario changing.

De novo BRCA1 mutation in a patient with breast cancer and an inherited BRCA2 mutation

Double heterozygotes for the Ashkenazi founder mutations in BRCA1 and BRCA2 genes

A breast cancer patient of Scottish descent with germ-line mutations in BRCA1 and BRCA2

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

Large genomic BRCA2 rearrangements and male breast cancer

Concomitant BRCA1 and BRCA2 gene mutations in an Ashkenazi Jewish woman with primary breast and ovarian cancer

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

Incidence of BRCA1 and BRCA2 mutations in young Korean breast cancer patients

BRCA2-null embryonic survival is prolonged on the BALB/c genetic background

Double Heterozygosity for BRCA1 Pathogenic Variant and BRCA2 Polymorphic Stop Codon K3326X: A Case Report in a Southern Italian Family

A cautionary note: false homozygosity for BRCA2 6174delT mutation resulting from a single nucleotide polymorphism masking the wt allele

Caucasian family with two independent mutations: 2594delC in BRCA1 and 5392delAG in BRCA2 gene

Presymptomatic breast cancer in Egypt: role of BRCA1 and BRCA2 tumor suppressor genes mutations detection.

The current social, political, and medical role of genetic testing in familial breast and ovarian carcinomas

Ethnic differences in cancer risk resulting from genetic variation

Prevalence of founder BRCA1 and BRCA2 mutations among breast and ovarian cancer patients in Hungary

Retinoblastoma and hypochondroplasia: a case report of two germline mutations arising simultaneously

Hereditary breast cancer; Genetic penetrance and current status with BRCA

A family with three germline mutations in BRCA1 and BRCA2

Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations.

Literature Review of BARD1 as a Cancer Predisposing Gene with a Focus on Breast and Ovarian Cancers.

Five Italian Families with Two Mutations in BRCA Genes.

Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination.

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

Related Concepts

Related Feeds

Carcinoma, Ductal

Breast Cancer: BRCA1 & BRCA2

Related Papers

A breast cancer patient of Scottish descent with germ-line mutations in BRCA1 and BRCA2

Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2

Association of BRCA1 with Rad51 in mitotic and meiotic cells

The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells