PMID: 7580869Aug 1, 1995Paper

A brief appraisal on some aspects of the receptor-receptor interaction

Neurochemistry International
L F AgnatiK Fuxe

Abstract

Receptor-receptor interaction is being recognized as a key cellular mechanism responsible for the integration of signals between different transmission lines at the membrane level. Receptor-receptor interaction extends the classical concept of integration of depolarization and hyperpolarization effects to the integration of chemical events at membrane level. In the present paper only some hypotheses on the possible mechanistic aspects of the interactions between the membrane receptors will be discussed. Furthermore, possible functional consequences of receptor-receptor interaction will be explored. The limitations of the present experimental approaches to the study of receptor-receptor interaction will also be analysed.

References

Jan 1, 1976·Biochemical Pharmacology·R E Buller, B W O'Malley
Dec 1, 1992·Neuroscience·S FerréB B Fredholm
Oct 1, 1989·Archives of Biochemistry and Biophysics·M Clagett-Dame, J F McKelvy
Sep 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·B GrasbergerH Metzger
Dec 1, 1984·Neuroscience·F O Schmitt
Jan 1, 1993·Molecular Neurobiology·M ZoliK Fuxe

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Citations

Sep 7, 2006·Journal of Neural Transmission·L F AgnatiK Fuxe
Apr 12, 2003·Pharmacology & Toxicology·Paul MicevychKevin Sinchak
Aug 5, 1998·The American Journal of Physiology·U HoltbäckA Aperia

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