A brief submaximal isometric exercise test 'unmasks' systolic and diastolic masked hypertension

Journal of Hypertension
Nikolaos KoletsosStella Douma

Abstract

An exaggerated blood pressure (BP) response during dynamic exercise testing has been proposed as an additional screening tool to identify systolic masked hypertension (masked-HYP). However, masked-HYP in young people is often characterized by an elevated DBP. Static/isometric exercise elicits augmented sympathetic stimulation causing greater increases in both SBP and DBP than dynamic exercise. To examine whether individuals with masked-HYP exhibit exaggerated BP responses during a submaximal handgrip vs. normotensive individuals and individuals with sustained hypertension (true-HYP), and the possible associations of exercise BP with total peripheral resistance (TPR), central/aortic BP, and 24-h-ambulatory BP (24-h BP). Eighty-six participants [untreated, newly diagnosed, masked-HYP (n = 27), true-HYP (n = 31), and normotensive individuals (n = 28); 46.3 ± 10.7 years], following evaluation of office BP, central/aortic BP, pulse wave velocity, carotid intima-media thickness, echocardiocardiography, and 24-h BP, underwent a 3-min handgrip (30% maximal voluntary contraction) with beat-by-beat BP and hemodynamics assessment (Finapres Medical Systems). Despite similar baseline-BP in masked-HYP and normotensive individuals, during exe...Continue Reading

References

Sep 15, 1990·The American Journal of Cardiology·M F WilsonW R Lovallo
Dec 1, 1989·Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension·P Lund-Johansen
Jun 1, 1988·Sports Medicine·P Palatini
Mar 1, 1984·The Journal of Hand Surgery·V MathiowetzN Kashman
Dec 7, 2002·Hypertension·Thomas G PickeringJoseph E Schwartz
Aug 6, 2003·Medicine and Science in Sports and Exercise·Cora L CraigPekka Oja
Apr 6, 2004·American Journal of Hypertension·Kerry J StewartPamela Ouyang
May 11, 2005·American Journal of Hypertension·Iddo Z Ben-DovMichael Bursztyn
Jun 1, 2005·American Journal of Hypertension·George S StergiouLeonidas G Roussias
Sep 27, 2006·European Heart Journal·Stephane LaurentUNKNOWN European Network for Non-invasive Investigation of Large Arteries
Feb 12, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·James H SteinUNKNOWN American Society of Echocardiography Carotid Intima-Media Thickness Task Force
Jul 19, 2008·Journal of the American College of Cardiology·Chi Young ShimNamsik Chung
Aug 14, 2008·Journal of Hypertension·Guillaume BobriePierre-François Plouin
Oct 1, 2008·The American Journal of Medicine·Costas TsioufisChristodoulos Stefanadis
Feb 7, 2009·International Journal of Clinical Practice·N TzemosT M MacDonald
Nov 17, 2010·Hypertension·Tine W HansenJan A Staessen
Nov 26, 2010·Clinical and Experimental Hypertension : CHE·Mehmet KayrakHasan Gok
Jan 13, 2011·The Journal of Physiology·Wanpen VongpatanasinGail D Thomas
Apr 1, 2011·Blood Pressure·Martin G SchultzJames E Sharman
Apr 29, 2011·American Journal of Hypertension·James E SharmanThomas H Marwick
Nov 18, 2011·American Journal of Hypertension·Ramón C HermidaJosé R Fernández
Sep 18, 2012·European Journal of Applied Physiology·Konstantina DiplaIoannis S Vrabas
Mar 8, 2013·Journal of Hypertension·Marjo-Riitta A HänninenAntti M Jula
Nov 12, 2013·American Journal of Physiology. Heart and Circulatory Physiology·Kazuhito WatanabeTakeshi Nishiyasu
Nov 19, 2013·Journal of the American College of Cardiology·Charalambos VlachopoulosChristodoulos Stefanadis
Jan 15, 2014·Hypertension·George S StergiouUNKNOWN International Database on HOme blood pressure in relation to Cardiovascular Outcome (IDHOCO) Investigators
Feb 6, 2014·European Heart Journal·José R BanegasBryan Williams
Jun 3, 2014·Journal of Hypertension·Gianfranco ParatiYuqing Zhang
Dec 4, 2014·American Journal of Hypertension·Cesare CuspidiGiuseppe Mancia
Apr 24, 2015·Journal of the American Heart Association·Assaf BergerElad Maor
Oct 13, 2015·Annals of Internal Medicine·Albert L Siu, UNKNOWN U.S. Preventive Services Task Force
Nov 12, 2015·BioMed Research International·Antonio CrisafulliShigehiko Ogoh
May 1, 2014·Pulse·Martin G Schultz, James E Sharman
Apr 5, 2016·High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension·Damiano Rizzoni

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