A bullous rash

Archives of Disease in Childhood. Education and Practice Edition
Vanessa MigliarinoEgidio Barbi

Abstract

A 3-year-old boy presented with a 5-day history of bullous skin lesions localised mainly in the upper and lower limbs and in the genital region (figure 1). Lesions were not pruritic nor painful and showed a central crust. There was no family history of skin disorders or autoimmune diseases. The child never had fever and his physical examination was otherwise unremarkable. edpract;archdischild-2020-319179v1/BLKF1F1BLK_F1Figure 1Bullous skin lesions forming around a central crust, localised in the upper and lower limbs. QUESTIONS: What is the most likely diagnosis based on this clinical presentation?Bullous impetigo.Bullous pemphigoid.Linear IgA bullous dermatosis.Dermatitis herpetiformis.What would be the next step in the investigation to confirm your diagnosis?Skin biopsy.Swab test for bacterial culture with an antibiogram.Anti-transglutaminase antibody detection.What is the mainstay of management?Dapsone.Systemic steroids.Topical steroids.All of the above answers are correct, according to the severity of the disease. Answers can be found on page 02 .

References

May 25, 2011·Dermatologic Clinics·Emily M Mintz, Kimberly D Morel
Sep 20, 2011·Dermatologic Clinics·Sue Yin Ng, Vanessa V Venning
Dec 6, 2011·Clinics in Dermatology·Giulio Fortuna, M Peter Marinkovich
Sep 27, 2013·Anais Brasileiros De Dermatologia·Fernanda Berti Rocha MendesVirgínica Scaff Gonçalves
Jan 16, 2014·Autoimmunity Reviews·Ruben KershenovichDaniel Mimouni
Apr 19, 2016·Pediatric Dermatology·Cathy Y ZhaoDedee F Murrell

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