PMID: 9430799Feb 7, 1998Paper

A carbohydrate meal attenuates the forearm vasoconstrictor response to lower body subatmospheric pressure in healthy young adults

Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society
M T KearneyI A Macdonald

Abstract

The cardiovascular (CV) responses to meal ingestion and orthostasis are well established. The effect of meal ingestion and meal composition on the CV responses to orthostasis are unknown. The effect of high carbohydrate (HC) and high fat (HF) meal ingestion on the CV responses to simulated orthostatic stress (using graded lower body subatmospheric pressure (LBSP)) was assessed in nine healthy young volunteers. Cardiac output (CO), forearm blood flow (FABF) heart rate (HR) and blood pressure (BP) were measured before and during LBSP while fasted and after eating HC and HF meals. Ingestion of both meals led to an increase in CO and HR. Both meals resulted in a fall in total peripheral resistance but only HC led to a significant fall in BP (p < 0.05). HF had no effect on the CV responses to LBSP, whereas HC resulted in attenuated FABF and forearm vascular resistance responses (p < 0.05). Thus, ingestion of an HC meal significantly attenuates the forearm vascular response to orthostatic stress and the hypotensive effect of orthostasis is additive to that occurring after an HC meal.

References

Jan 15, 1992·The American Journal of Cardiology·S M RyanL A Lipsitz
Jun 1, 1991·The Journal of Clinical Investigation·E A AndersonA L Mark
Nov 1, 1989·The Journal of Clinical Investigation·C BerneF Niklasson
Jun 1, 1989·British Heart Journal·H KelbaekJ Godtfredsen
Jan 1, 1988·Annual Review of Physiology·B G Wallin, J Fagius
Jul 1, 1974·Physiological Reviews·R A WolthuisA E Nicogossian
Nov 1, 1972·The Journal of Clinical Investigation·R P ZollerD D Heistad
Feb 1, 1980·Age and Ageing·K J CollinsD J Oliver
Apr 1, 1995·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·H P SchobelD W Ferguson
Feb 15, 1995·The Journal of Physiology·J A TaylorD L Eckberg
Jan 1, 1993·The American Journal of Cardiology·J F SneddonA J Camm
Jul 1, 1953·The Journal of Physiology·R J WHITNEY
May 1, 1963·British Medical Bulletin·A D GREENFIELDJ F MOWBRAY

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Citations

Aug 22, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·A S ObermanL A Lipsitz
Sep 26, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·L K SummersK N Frayn

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