A Case-and-Control, Multisite, Positive Controlled, Prospective Study of the Safety and Effectiveness of Immediate Inferior Alveolar Nerve Processed Nerve Allograft Reconstruction With Ablation of the Mandible for Benign Pathology

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
John R ZunigaDaniel Petrisor

Abstract

This study determined whether immediate reconstruction of the inferior alveolar nerve with a long (>4.5 cm) processed nerve allograft (PNA) in conjunction with simultaneous ablation and reconstruction of the mandible would be effective in safely restoring subjective sensation and achieving functional sensory recovery. Patients (5 to 70 yr old) requiring resection of the unilateral or bilateral mandible for benign pathology were included. The graft had to be longer than 4.5 cm. Results of sensory nerve tests and 3 different surveys (Direct Path, Numerical Rating Scale, Word Choice) were collected before surgery and at 3, 6, and 12 months after surgery. Safety data were recorded. Twenty-six patients participated in this study. Three patients served as positive controls (no nerve repair). Five in the repair group and 1 in the positive control group were lost to follow-up. Data during a 1-year period were collected on 18 patients (7 male and 11 female; mean age, 26.4 yr; range, 10 to 64 yr). The mean length of the PNA was 62.7 mm (range, 45 to 70 mm). Seventeen of 18 patients had S4 sensory scores preoperatively and the postoperative score was S4 at 3 months in 3, at 6 months in 3, and at 1 year in 12. Scores for positive control p...Continue Reading

References

Dec 20, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Shahrokh C BagheriMartin B Steed

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Citations

Jul 31, 2018·Ophthalmic Plastic and Reconstructive Surgery·Ilya M LeyngoldChristopher Weller
Jun 26, 2020·Advanced Healthcare Materials·Mary KasperChristine E Schmidt
Mar 19, 2019·Plastic and Reconstructive Surgery. Global Open·Ivica DucicUros Ahcan
Jun 17, 2020·Plastic and Reconstructive Surgery. Global Open·Ivica DucicKyle R Eberlin
Dec 23, 2020·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Roger A Meyer
Dec 29, 2020·Facial Plastic Surgery : FPS·Scott D Morgan, John R Zuniga
Jan 1, 2021·Seminars in Plastic Surgery·Daniel Perez, Edward Ellis
Feb 15, 2021·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Michael MiloroRoger A Meyer
Dec 20, 2020·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·A ManfusoC Copelli
Mar 7, 2021·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Keith A SonneveldShahrokh C Bagheri
Apr 16, 2021·Case Reports in Plastic Surgery & Hand Surgery·Abelardo MedinaQuynh Nguyen
May 3, 2021·Journal of Stomatology, Oral and Maxillofacial Surgery·Mélanie Le DonneNicolas Sigaux
Aug 28, 2021·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Roger A Meyer

Aug 29, 2021·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·John R Zuniga

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