A case-control study of sociodemographic and geographic characteristics of 335 children with eosinophilic esophagitis

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
James P FranciosiJonathan M Spergel

Abstract

The epidemiology of pediatric eosinophilic esophagitis (EE) is poorly characterized. In this study, we aimed to determine demographic, socioeconomic, and geographic characteristics of our cohort of EE children. A case-control design was used to compare 335 EE subjects with control subjects from gastroenterology (GI) and allergy clinics as well as 2000 U.S. census data. EE subjects were significantly different than the greater Philadelphia population as well as control subjects from our gastroenterology and allergy clinics. EE subjects were 83.6% Caucasian, compared with 70.9% of GI control subjects (odds ratio [OR], 2.17; P < .001; confidence interval [CI], 1.52-3.11), 64.9% of allergy control subjects (OR, 2.83; P < .001; CI, 1.99-4.04), and 73.0% of the greater Philadelphia population. EE subjects were 75.8% male, compared with 48.0% of GI control subjects (OR, 3.39; P < .001; CI, 2.47-4.65), 60.4% of allergy control subjects (OR, 1.62; P < .001; CI, 1.19-2.19), and 48.0% of the greater Philadelphia population. We initially demonstrated that EE subjects are more affluent, more educated, and reside more often in suburban areas. However, Caucasian race was a significant confounding variable and accounted for socioeconomic or ge...Continue Reading

References

Feb 14, 2002·The Journal of Allergy and Clinical Immunology·Jonathan M SpergelChris A Liacouras
Dec 20, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Chris A LiacourasJonathan E Markowitz
Feb 3, 2006·The Journal of Clinical Investigation·Carine BlanchardMarc E Rothenberg
Jun 1, 2006·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Susan A HallThomas C Ricketts
Aug 1, 2006·Archives of Disease in Childhood·S CherianD A Forbes
Aug 22, 2006·American Journal of Epidemiology·Chris GreenCharles N Bernstein
Nov 8, 2006·The Journal of Allergy and Clinical Immunology·Carine BlanchardMarc E Rothenberg
Jan 30, 2007·The Journal of Allergy and Clinical Immunology·Amal H Assa'adMarc E Rothenberg
Jan 30, 2007·Gastrointestinal Endoscopy·David A Katzka
May 10, 2007·Archives of Pathology & Laboratory Medicine·Andrew D VanderheydenFrank A Mitros
Jun 19, 2007·The American Journal of Gastroenterology·Rupa GillYoram Elitsur

❮ Previous
Next ❯

Citations

Sep 26, 2012·Nature Reviews. Gastroenterology & Hepatology·Alex Straumann, Alain M Schoepfer
Jan 25, 2012·Journal of Pediatric Psychology·Tiffany H TaftLaurie Keefer
Oct 3, 2009·Current Opinion in Pediatrics·Amy E Pattishall, Nancy D Spector
Jul 3, 2013·Archives of Disease in Childhood·J M E Fell
Sep 13, 2012·World Journal of Gastroenterology : WJG·Yoram Elitsur
Feb 6, 2013·World Journal of Gastroenterology : WJG·Evan S DellonMogens Vyberg
Aug 23, 2012·World Journal of Gastrointestinal Endoscopy·Cristina Targa Ferreira, Helena As Goldani
May 9, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Thomas WeilerHemant Sharma
Oct 9, 2015·Scandinavian Journal of Gastroenterology·Iain Alexander MurrayMichael Schultz
Oct 17, 2015·Expert Review of Gastroenterology & Hepatology·Antonella CianferoniAmanda Muir
Jan 14, 2016·Current Allergy and Asthma Reports·David A Hill, Jonathan M Spergel
May 13, 2014·Gastroenterology Clinics of North America·Evan S Dellon
Dec 18, 2013·The Journal of Allergy and Clinical Immunology·Rupinder K GillSteven M Schwarz
Feb 26, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Melanie A RuffnerJonathan M Spergel
Mar 5, 2013·Gastroenterology Clinics of North America·Evan S Dellon
Oct 3, 2012·Gastrointestinal Endoscopy·Mohammed Aamir AliLysandra Voltaggio
Jun 30, 2012·The Journal of Allergy and Clinical Immunology·Jonathan M SpergelChris A Liacouras
Jun 26, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Evan S Dellon
Jun 4, 2011·The Journal of Allergy and Clinical Immunology·Charles W DeBrosseMarc E Rothenberg
May 17, 2011·The Journal of Allergy and Clinical Immunology·Joseph D Sherrill, Marc E Rothenberg
Apr 8, 2010·The Journal of Allergy and Clinical Immunology·Julie M CaldwellMarc E Rothenberg
Sep 8, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Evan S DellonNicholas J Shaheen
Dec 4, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·David A Katzka
Jul 15, 2015·The Journal of Allergy and Clinical Immunology. in Practice·Susan KimJaved Sheikh
Nov 11, 2015·Best Practice & Research. Clinical Gastroenterology·Elizabeth T Jensen, Evan S Dellon
Nov 11, 2015·Best Practice & Research. Clinical Gastroenterology·Ralf G Heine
Nov 13, 2013·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·D A RybnicekE S Dellon
Jul 6, 2014·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H PhilpottP R Gibson
Aug 12, 2014·Gastroenterology·Evan S Dellon, Chris A Liacouras
Jan 3, 2014·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Y-J LeeR Schey
Jul 25, 2015·Current Gastroenterology Reports·Thomas M Runge, Evan S Dellon
Aug 4, 2015·Current Allergy and Asthma Reports·Antonella Cianferoni, Jonathan M Spergel
Jul 22, 2015·Clinical Reviews in Allergy & Immunology·Antonella Cianferoni, Jonathan Spergel
Jul 24, 2010·Orvosi hetilap·Dóra Lippai, Zsolt Tulassay
Oct 23, 2009·Allergology International : Official Journal of the Japanese Society of Allergology·Antonella Cianferoni, Jonathan M Spergel
Aug 26, 2014·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Daniel ChathamJay A Lieberman
Oct 23, 2012·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Jennifer L GoralskiEvan S Dellon
Apr 5, 2014·Gut·Alex Straumann, Alain Schoepfer
Feb 23, 2017·Mucosal Immunology·L C Kottyan, M E Rothenberg
Feb 18, 2010·Expert Review of Clinical Immunology·Terri F Brown-Whitehorn, Jonathan M Spergel
Feb 6, 2017·Asia Pacific Allergy·Hamish PhilpottFrancis Thien
Feb 9, 2016·World Journal of Gastrointestinal Pharmacology and Therapeutics·Michele Pier Luca GuarinoJose Behar
Oct 6, 2011·The American Journal of Gastroenterology·Sarah Lw SperryEvan S Dellon
Sep 22, 2018·Current Opinion in Pediatrics·Melanie A Ruffner, Jonathan M Spergel
Aug 26, 2015·The American Journal of Gastroenterology·Evan S DellonNicholas J Shaheen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.

Related Papers

Journal of Pediatric Gastroenterology and Nutrition
Jonathan M SpergelC A Liacouras
The Journal of Allergy and Clinical Immunology
Amal H Assa'adMarc E Rothenberg
The Journal of Clinical Investigation
Carine BlanchardMarc E Rothenberg
The New England Journal of Medicine
Richard J NoelMarc E Rothenberg
© 2021 Meta ULC. All rights reserved