A case-control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD)

Arquivos de neuro-psiquiatria
Francisco de Assis Aquino GondimErick L Messias

Abstract

Neurological diseases are common in inflammatory bowel disease (IBD) patients, but their exact prevalence is unknown. Method We prospectively evaluated the presence of neurological disorders in 121 patients with IBD [51 with Crohn's disease (CD) and 70 with ulcerative colitis (UC)] and 50 controls (gastritis and dyspepsia) over 3 years. Results Our standard neurological evaluation (that included electrodiagnostic testing) revealed that CD patients were 7.4 times more likely to develop large-fiber neuropathy than controls (p = 0.045), 7.1 times more likely to develop any type of neuromuscular condition (p = 0.001) and 5.1 times more likely to develop autonomic complaints (p = 0.027). UC patients were 5 times more likely to develop large-fiber neuropathy (p = 0.027) and 3.1 times more likely to develop any type of neuromuscular condition (p = 0.015). Conclusion In summary, this is the first study to prospectively establish that both CD and UC patients are more prone to neuromuscular diseases than patients with gastritis and dyspepsia.

References

Apr 1, 1976·Journal of Neurology, Neurosurgery, and Psychiatry·A Coxon, C A Pallis
Feb 1, 1991·Scandinavian Journal of Gastroenterology·D StåhlbergA Persson
Mar 1, 1995·Neurology·A LossosI Steiner
Jun 1, 1997·Southern Medical Journal·A Elsehety, T E Bertorini
Feb 12, 2005·Brain : a Journal of Neurology·F A A GondimN Latov
Sep 7, 2005·Gastroenterology·Edward V Loftus
Jul 4, 2009·Inflammatory Bowel Diseases·Leonard B WeinstockArthur S Walters
Aug 15, 2009·Scandinavian Journal of Gastroenterology·Samia Ben SassiFayçal Hentati
Apr 5, 2011·Gut and Liver·Züleyha Akkan CetinkayaTülin Tanrıdağ
Mar 17, 2012·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Q Lei, A P Malykhina
Apr 28, 2012·Journal of Clinical Neuromuscular Disease·Ting-Chin David ShenPeter H R Green
Nov 7, 2012·Headache·Alexandra K DimitrovaPeter H Green
Dec 21, 2012·European Journal of Gastroenterology & Hepatology·Asimenia BabaliGeorgios Kouklakis
Apr 12, 2013·Neurology·Juan J FigueroaChristopher J Klein
Sep 14, 2013·European Journal of Internal Medicine·Aristeidis H KatsanosEpameinondas V Tsianos
Dec 5, 2013·Scandinavian Journal of Gastroenterology·Jan StovicekRadan Keil
Feb 28, 2014·World Journal of Gastroenterology : WJG·Germán Morís

❮ Previous
Next ❯

Citations

Jul 28, 2015·European Journal of Internal Medicine·Carmen García-Cabo, Germán Morís
Jul 7, 2015·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·F de Assis Aquino Gondim, F Patrick Thomas
Feb 14, 2016·Muscle & Nerve·Francisco de Assis A GondimAndré L Pinheiro Borges
Jun 2, 2017·Continuum : Lifelong Learning in Neurology·Ronald F Pfeiffer
May 23, 2015·Inflammatory Bowel Diseases·Francisco de A A GondimFrancisco H Rola
Jul 17, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Antônio M F LeitãoFrancisco De A A Gondim

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrophic Gastritis

Atrophic Gastritis is a process where gastric glandular cells are lost and replaced with firbous tissues, as a result of chronic inflammation. Learn more about Atrophic Gastritis here.