PMID: 8902485Oct 1, 1996

A case for serial examination of sputum inflammatory cells

The European Respiratory Journal
A G WongF E Hargreave

Abstract

In the case reported, serial evaluation of sputum inflammatory cell counts made it possible to identify an unusual series of events in a man with eosinophilic bronchitis. The patient initially presented with a productive cough, which did not respond to treatment with antibiotics or high-dose inhaled corticosteroids. A diagnosis of eosinophilic bronchitis was made after demonstration of intense sputum eosinophilia. When inhaled corticosteroids were stopped, symptoms and sputum eosinophilia became worse and airway hyperresponsiveness developed. Both abnormalities were reversed by a course of prednisone. When the prednisone was stopped the productive cough recurred but on this occasion sputum examination suggested a different disease process and the symptoms resolved after a course of co-trimoxazole. The patient has subsequently remained well on no treatment with little or no sputum eosinophilia.

Citations

May 1, 1997·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·F E Hargreave
Aug 3, 1999·American Journal of Respiratory and Critical Care Medicine·C E BrightlingI D Pavord
Nov 11, 1999·American Journal of Respiratory and Critical Care Medicine·F E Hargreave, R Leigh
Sep 16, 2000·American Journal of Respiratory and Critical Care Medicine·C E BrightlingI D Pavord
Dec 22, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C E Brightling, I D Pavord
Dec 12, 2000·The Journal of Allergy and Clinical Immunology·C LemièreQ Hamid
Nov 22, 2000·Annals of Medicine·C E Brightling, I D Pavord
Nov 21, 2014·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Thiago Mamôru SakaeEmílio Pizzichini
May 17, 2002·The Korean Journal of Internal Medicine·Jae Hak JooChoon Sik Park

Related Concepts

Microbicides
Anti-Inflammatory Agents
Asthma
Bronchitis
Coughing
Differential Diagnosis
Eosinophilia, Tropical
Eosinophil
Glucocorticoid Effect
Differential White Blood Cell Count Procedure

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