A case of acute necrotizing encephalopathy associated with parainfluenza virus infection.

Korean journal of pediatrics
Yoo-Na Kim, Su Jeong You

Abstract

Acute necrotizing encephalopathy (ANE) may be suspected when a young child presents with abrupt onset of altered mental status, seizures, or both. Definitive clinical diagnosis is based on magnetic resonance imaging (MRI) results. ANE is associated with influenza virus infections. Preliminary data suggests that up to 25% of ANE patients die, and up to 25% of ANE survivors develop substantial neurologic sequelae. Here, we describe a case of a comatose 22-month-old girl who was admitted to our hospital because of febrile illness and seizures. On day 13 of her illness, she died from ANE associated with infection from parainfluenza virus. Brain MRI results indicated diffuse bilateral symmetric signal changes in both basal ganglia, thalami, periventricular white matter, pons, and cerebral white matter, as well as generalized swelling of the brain.

References

Sep 1, 1973·Archives of Neurology·H C PowellB McKellar
May 1, 1995·Journal of Neurology, Neurosurgery, and Psychiatry·M MizuguchiS Kamoshita
Aug 1, 1994·The Pediatric Infectious Disease Journal·M A JacksonV F Burry
Jun 22, 2001·Journal of Child Neurology·S RavidL Eviatar
Mar 14, 2002·Brain & Development·Konstantinos A VoudrisAngeliki Skardoutsou
Jul 25, 2003·Pediatric Neurology·Mona SazgarD Barry Sinclair
Sep 19, 2003·Journal of Child Neurology·Sotiria D MastroyianniAngeliki Skardoutsou

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Citations

Apr 16, 2015·Mediators of Inflammation·Xiujuan WuHong-Liang Zhang
Jun 4, 2016·Brain & Development·Hwee Ying LimDerrick Wei Shih Chan
May 16, 2017·Child Neurology Open·Adina AchiriloaieRavi Raghavan
Dec 4, 2020·Microbiology and Immunology·Mohammad FarahmandMohammad Shayestehpour

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