PMID: 16502500Feb 28, 2006Paper

A case of acute ventricular capture threshold rise associated with flecainide acetate

Yonsei Medical Journal
Tae Soo KangHyun-Seung Kim

Abstract

Antiarrhythmic agents may increase capture threshold, but this is rarely of clinical significance. Flecainide acetate, a class IC agent, is reported to have a significant effect on the myocardial capture threshold. In this presentation, we report the case of a 72-year-old male, with a previously implanted VVI pacemaker due to sick sinus syndrome, who was treated with flecainide acetate for paroxysmal atrial arrhythmia control. During the fifteenth day of treatment, an abrupt rise in the ventricular capture threshold with ventricular pacing failure was noted. The capture threshold decreased two days after discontinuation of flecainide acetate.

References

Nov 1, 1985·Pacing and Clinical Electrophysiology : PACE·P R WalkerL M Clarke
Sep 1, 1983·Pacing and Clinical Electrophysiology : PACE·K J HellestrandA J Camm
Mar 1, 1997·The Journal of Laboratory and Clinical Medicine·J F AloiaE Flaster
Jul 31, 2001·Pacing and Clinical Electrophysiology : PACE·D AntonelliT Rosenfeld
Jun 7, 2002·Pacing and Clinical Electrophysiology : PACE·Helio Fornieles-PérezOscar Sanz
Dec 17, 2003·Pacing and Clinical Electrophysiology : PACE·Charles KennergrenUNKNOWN Study Group

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Citations

Feb 6, 2020·Pacing and Clinical Electrophysiology : PACE·Michael JiangNishant Verma
Feb 18, 2020·Pacing and Clinical Electrophysiology : PACE·Youssef Jalloul, Marwan M Refaat

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