PMID: 3756313Jan 1, 1986Paper

A case of amiodarone-induced hyperthyroidism and hepatitis: results of clinical laboratory and histological tests

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
G GayF Zannad

Abstract

We report a case of amiodarone-induced hepatitis accompanied by hyperthyroidism in which estimations of amiodarone in blood and in the liver and histological examinations were performed at the start and end of a 3-month interval. Our observation demonstrates the persistence in the liver of amiodarone and its principal metabolite for 3 months after the drug was withdrawn. There was no correlation between the persistence of the drug, the elevation of enzyme levels, and the extent of histological damage in the liver.

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