A case of anaphylactic shock with tranexamique acid (Exacyl)

Annales Françaises D'anesthèsie Et De Rèanimation
M-M Lucas-PolomeniC Ecoffey

Abstract

A 72-year-old male patient was scheduled for coronary artery bypass graft surgery because of severe three-vessel disease. Induction of anaesthesia was uneventful. Following bolus infusion of tranexamic acid (Exacyl), the patient presented clinical signs consistent with anaphylactic shock. Surgery was postponed and the patient recovered without sequaelae. Allergological investigations (cutaneous tests, serum IgE concentrations, in vitro histamine-release tests) suggest that this is the first reported case of anaphylactic shock to tranexamic acid. Several weeks later, the patient underwent surgery with a similar anaesthetic regimen and the clinical course was uneventful.

References

Jul 4, 2001·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·Y UozakiT Misaki
Dec 1, 1996·American Journal of Therapeutics·Robert W. Barrons, Jonathan S. Jahr

❮ Previous
Next ❯

Citations

Sep 4, 2009·Der Anaesthesist·C F WeberK Görlinger
Jul 16, 2010·Pharmacy World & Science : PWS·Selene ImbesiSebastiano Gangemi
Feb 27, 2013·Journal of Cosmetic Dermatology·Tsz Wah Tse, Edith Hui
Jan 25, 2017·The Journal of Allergy and Clinical Immunology. in Practice·Philip H LiKrzysztof Rutkowski
Mar 23, 2017·Paediatric Anaesthesia·Jennifer ChiemNathalia Jimenez
Mar 1, 2013·The Annals of Pharmacotherapy·Maider Pretel IrazabalMiguel Angel Idoate Gastearena
Oct 29, 2017·Journal of Orthopaedic Surgery and Research·Lu-Kai ZhangZheng-Rui Fan
Sep 11, 2020·Clinical and Molecular Allergy : CMA·Giuseppe MurdacaSebastiano Gangemi
Feb 28, 2008·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Ian S FraserAndrea S Lukes
Nov 23, 2016·Case Reports in Immunology·R A BansalA S Bansal
Aug 14, 2019·The Journal of Veterinary Medical Science·Jin-Young ChoiHyun-Jung Han
Sep 11, 2020·JBJS Case Connector·Scott PlasterAntony Kallur Antony
Jan 7, 2021·Foot & Ankle Specialist·William L JohnsTyler A Gonzalez
Oct 12, 2010·Journal of Pediatric and Adolescent Gynecology·Sameh Mikhail, Peter Kouides

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

Related Papers

Journal of Cardiothoracic and Vascular Anesthesia
Reza Jalaeian TaghaddomiAbbas Shirdel
The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi
Y UozakiT Misaki
© 2022 Meta ULC. All rights reserved